Evidence map›Paper›PMID 40160974›Full record

ArticleJTO clinical and research reports2025

Longitudinal Tracking of

Simon Heeke, Saumil Gandhi, Hai T Tran, Vincent K Lam, Lauren A Byers, Don L Gibbons, Carl M Gay, Mehmet Altan, Mara B Antonoff, Xiuning Le and 12 more

Abstract read
In one paragraph

Article in JTO clinical and research reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Simon HeekeDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Saumil GandhiDepartment of Radiation Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Hai T TranDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Vincent K LamSidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, Maryland.
Lauren A ByersDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Don L GibbonsDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Carl M GayDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Mehmet AltanDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Mara B AntonoffDepartment of Thoracic and Cardiovascular Surgery, UT MD Anderson Cancer Center, Houston, Texas.
Xiuning LeDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Janet TuDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Maliazurina B SaadDepartment of Imaging Physics, UT MD Anderson Cancer Center, Houston, Texas.
Michelle PekLucence Health Inc., Palo Alto, California.
Jonathan PohLucence Diagnostics Pte Ltd., Singapore.
Kao Chin NgeowLucence Diagnostics Pte Ltd., Singapore.
Anne TsaoDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Tina CasconeDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Marcelo V NegraoDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Jia WuDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
George R BlumenscheinDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
John V HeymachDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.
Yasir Y ElaminDepartment of Thoracic Head & Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although the administration of tyrosine-kinase inhibitors in Methods: We retrospectively analyzed 86 plasma samples from 33 patients enrolled in the BRIGHTSTAR clinical trial assessing local consolidative therapy (LCT) and brigatinib in patients with stage IV or recurrent NSCLC and confirmed Results: Conclusions: The inclusion of ctRNA in liquid biopsies increased detection of

Indexed as

ALKctDNActRNALiquid biopsyNSCLC

Identifiers

PMID40160974
PMCPMC11952838

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.