Evidence map›Paper›PMID 40160882›Full record

ArticleInternational cancer conference journal2025

Malignant transformation of an ovarian mature teratoma diagnosed 17 years ago: a case report and literature review of treatment with immune checkpoint inhibitors.

Akiho Nagayama, Chiho Miyagawa, Yoko Kashima, Mamiko Ohta, Tomoyuki Otani, Takashi Kurosaki, Kohsuke Isomoto, Chiaki Inagaki, Takayuki Takahama, Kimio Yonesaka and 5 more

Abstract read
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In one paragraph

Article in International cancer conference journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Akiho NagayamaDepartment of Obstetrics and Gynecology, Chibune General Hospital, 3-2-39 Fukumachi, Nishiyodogawa- Ku, Osaka, 555-0034 Japan.
Chiho MiyagawaDepartment of Obstetrics and Gynecology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.ORCID 0000-0002-9614-0117
Yoko KashimaDepartment of Obstetrics and Gynecology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Mamiko OhtaDepartment of Obstetrics and Gynecology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Tomoyuki OtaniDepartment of Pathology, Yachiyo Hospital, 2-2-7 Sumiyoshi-Cho, Anjo, Aichi 446-8510 Japan.
Takashi KurosakiDepartment of Medical Oncology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Kohsuke IsomotoDepartment of Medical Oncology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Chiaki InagakiDepartment of Medical Oncology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Takayuki TakahamaDepartment of Medical Oncology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Kimio YonesakaDepartment of Medical Oncology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Hidetoshi HayashiDepartment of Medical Oncology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Kazuko SakaiDepartment of Genome Biology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Kazuto NishioDepartment of Genome Biology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Kazuhiko NakagawaGenome Medical Center, Kindai University Hospital, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511 Japan.
Noriomi MatsumuraDepartment of Obstetrics and Gynecology, Kindai University, 377-2 Ohnohigashi, Osaka-Sayama, Osaka, 589-8511 Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 69-year-old multiparous postmenopausal woman had undergone bilateral total hip arthroplasty 17 years ago. Computed tomography showed a mature teratoma of 10 cm in the pelvis. Subsequently, she presented with symptoms of hoarseness and weight loss, along with evidence of malignant transformation of the same tumor in the pelvis and multiple enlarged lymph nodes. Bilateral adnexectomy was performed via laparotomy, yet peritoneal dissemination persisted. The ovarian tumor's histopathological diagnosis was mature teratoma with squamous cell carcinoma. Additionally, the mediastinal lymph nodes biopsy revealed poorly differentiated carcinoma. Comprehensive genomic profiling testing of the ovarian tumor showed pathogenic variants of Supplementary Information: The online version contains supplementary material available at 10.1007/s13691-024-00740-z.

Indexed as

Dermoid cystGenetic testingImmune checkpoint inhibitorOvarian cancerSquamous cell carcinomaTeratoma

Identifiers

PMID40160882
PMCPMC11950470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.