ArticleACS omega2025
Exposure of Polystyrene Micro- and Nanoplastics to Simulated Human Digestive Enzymatic Systems: Structural and Functional Implications.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Microplastics and Nanoplastics in the Human Diet: Sources of Exposure, Bioavailability, Toxicokinetics, and Systemic Health Effects.Molecules (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current in vitro study explores the exposure of the emerging pollutants polystyrene micro- and nanoplastics (PS-MNPs) within the digestive system and their interaction with key digestive enzymes such as α-amylase, pepsin, and pancreatin. The present research aims to elucidate the potential health implications of digestive enzymes by PS-MNPs based on the previously estimated mean of ingested microplastics (MPs) (0.714 g/day). The study deepens our understanding of the environmental pollutants' impact on human health by examining the interactions between polystyrene (PS) microplastics (PS MPs, 37-50 μm approx.) and PS nanoplastics (PS NPs, 100 nm) with digestive enzymes. The study analyzes the effects of micro- and nanosized plastics on enzyme activity using multiple spectroscopic techniques, revealing the molecular mechanisms of enzyme inhibition and structural changes caused by PS NPs, more than those by PS MPs. The fluorescence emission spectra indicated a static quenching mechanism across all the digestive enzymes at
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Registered trials
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