Evidence map›Paper›PMID 40160673›Full record

ArticleQuantitative imaging in medicine and surgery2025

Estimation of hypoperfused tissue volume in large vessel occlusions: pseudo-continuous arterial spin labeling versus dynamic susceptibility contrast perfusion-weighted imaging.

Chenxi Zhao, Chen Cao, Lei Ren, Huiying Wang, Gemuer Wu, Dingwei Fu, Jinxia Zhu, Chao Chai, Yu Guo, Shuang Xia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chenxi Zhao *Department of Radiology, The First Central Clinical School, Tianjin Medical University, Tianjin, China.
Chen Cao *Department of Radiology, Tianjin Huanhu Hospital, Tianjin, China.
Lei Ren *Medical Imaging Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Huiying WangDepartment of Radiology, Medical Imaging Institute of Tianjin, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin, China.
Gemuer WuDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Dingwei FuDepartment of Radiology, The First Central Clinical School, Tianjin Medical University, Tianjin, China.
Jinxia ZhuMR Collaboration, Siemens Healthineers Ltd., Beijing, China.
Chao ChaiDepartment of Radiology, Medical Imaging Institute of Tianjin, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin, China.
Yu GuoDepartment of Radiology, Medical Imaging Institute of Tianjin, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin, China.
Shuang XiaDepartment of Radiology, Medical Imaging Institute of Tianjin, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Currently, the selection of patients with acute anterior large vessel occlusions (LVOs) for endovascular thrombectomy (EVT) is primarily based on dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) or computed tomography (CT) perfusion imaging. This study investigated the consistency between hypoperfused tissue (HPT) (time to maximum >6 s, Tmax >6 s) volumes estimated by corrected and uncorrected multidelay pseudo-continuous arterial spin labeling (pCASL) and DSC-PWI in patients with anterior LVOs and also evaluated the diagnostic performances in selecting patients with acute LVOs for EVT. Methods: This retrospective study enrolled patients with acute (n=108) and symptomatic chronic (n=90) LVOs. Shapiro-Wilk tests and receiver operating characteristic (ROC) analyses were used. Intraclass correlation coefficient (ICC) compared the consistency of HPT volume calculated by DSC-PWI and multidelay pCASL. Results: Multidelay pCASL with different thresholds in acute LVOs were 128.8 [interquartile range (IQR), 76.2-181.1] mL in uncorrected relative cerebral blood flow (rCBF) <40%, 84.1 (IQR, 36.8-133.9) mL in uncorrected CBF <20 mL·100 g Conclusions: The volume of HPT defined by corrected CBF <20 mL·100 g

Indexed as

Acute ischemic stroke (AIS)arterial spin labeling (ASL)hypoperfused tissue volumelarge vessel occlusions (LVOs)

Identifiers

PMID40160673
PMCPMC11948376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.