ArticleQuantitative imaging in medicine and surgery2025
The diagnostic value of ultra-microangiography for biliary atresia.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Multimodal Ultrasound Characterization of a Testicular Leydig Cell Tumor With Emphasis on Microvascular Flow Imaging Findings: A Case Report and Literature Review.Journal of clinical ultrasound : JCU · 2026Review
- Quantitative Ultrasound Assessment of Skeletal Muscle Microvascularity in Relation to Serum 25-Hydroxyvitamin D Concentrations.Diagnostics (Basel, Switzerland) · 2026Article
- The value of multimodal ultrasound imaging in differentiating HER2-positive breast cancer.Frontiers in oncology · 2026Article
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5 authors.
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Abstract
Background: Color Doppler flow imaging (CDFI) has auxiliary diagnostic value for biliary atresia (BA), as it can detect positive blood flow signals under the liver capsule; however, it has low sensitivity and is easily affected by respiration. Ultra-microangiography (UMA) is a microvascular imaging technique that focuses on low-speed blood flow, and can display microvascular structures that traditional CDFI cannot. This study aimed to explore the application value of UMA in the diagnosis of BA by analyzing and comparing the microvascular detection capabilities of CDFI and UMA in infants with BA. Methods: A retrospective study of 52 infants diagnosed with BA via intraoperative cholangiography or surgical exploration at Shandong Provincial Hospital Affiliated to Shandong First Medical University between January 2022 and February 2024 was conducted. An additional 105 newborns and infants with similar gender ratios and ages admitted to the hospital for jaundice were included in the study as control subjects. Prior to treatment, all subjects underwent two-dimensional ultrasonography, CDFI, and UMA to measure the microvascular color pixel percentage (CPP) under the liver capsule. The subjects' clinical laboratory information, including age, weight, gamma-glutamyl transpeptidase (GGT), total bilirubin (TB), and direct bilirubin (DB), was collected. The independent sample Results: There was no significant difference between the two groups in terms of age and weight (P=0.057 and 0.613, respectively). The hepatic artery diameter, GGT, TB, and DB of the BA group were significantly higher than those of the control group (P=0.007, 0.005, 0.003, and 0.001, respectively). The maximum length and width of the gallbladder of the BA group were significantly lower than those of the control group (P=0.005 and 0.001, respectively). The CPP Conclusions: UMA better displayed the microvasculature than CDFI, and combined with other signs, it had better auxiliary diagnostic value for BA.
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