ArticleQuantitative imaging in medicine and surgery2025
Improved visualization of electron-density dual-energy computed tomography for lumbar disc disease over the standard gray-scale type and virtual noncalcium imaging.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Comparison of clinical efficacy and minimal invasiveness between unilateral biportal endoscopic and percutaneous endoscopic lumbar discectomy in the treatment of calcified lumbar disc herniation: a retrospective analysis.BMC musculoskeletal disorders · 2026Article
- Temporal bone dual-layer detector dual-energy computed tomography for identifying cholesteatoma.European radiology · 2026Article
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Abstract
Background: Dual-energy computed tomography (DECT) enhances tissue imaging characterization. However, no studies have evaluated the diagnostic accuracy of electron density (ED) for simultaneously displaying the lumbar disc and disc calcification. This retrospective study aimed to investigate the ability of ED to visualize lumbar disc disease as compared with standard computed tomography (SC) and virtual noncalcium (VNCa) imaging in order to provide a viable alternative for lumbar disc disease. Methods: From October 2023 to February 2024, we retrospectively analyzed data from 53 patients who underwent DECT and 3.0-T magnetic resonance imaging (MRI) within 2 weeks. The randomized SC, VNCa, and ED image sets were independently evaluated by four radiologists for visualization of the lumbar disc and disc calcification with an 8-week interval. Final disc calcification results were obtained by consensus, with the SC results serving as the reference standard. Two other experienced radiologists performed MRI evaluations as the lumbar disc reference standard. Diagnostic performance was compared for each image. Results: Among the 298 included lumbar discs, 183 lumbar disc herniations and bulges were revealed on MRI. As compared with VNCa and SC, ED showed higher overall sensitivity (91.3% Conclusions: ED demonstrated higher diagnostic accuracy and confidence for visualizing the lumbar disc and disc calcification on the computed tomography (CT) images as compared to VNCa and SC.
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