ArticleReviews in cardiovascular medicine2025
Association between the Clinical Frailty Scale and Neurological Outcomes in Out-of-Hospital Cardiac Arrest: A Retrospective Study.
Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Impact of frailty on mortality, functional outcome, and health status after out-of-hospital cardiac arrest: insights from the TTM2-trial.Intensive care medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Frailty is a physical condition characterized by increased vulnerability to external stressors. This study investigated the impact of premorbid frailty, as measured by the Clinical Frailty Scale (CFS), on neurological prognosis in patients with out-of-hospital cardiac arrest (OHCA). Methods: This is a single-center retrospective study. Data from 2006 to 2020 were analyzed for 595 adult OHCA patients admitted to the intensive care unit of National Taiwan University Hospital following resuscitation. Variables included demographics, medical history, resuscitation details, post-resuscitation data, and frailty assessments based on CFS. The primary outcome was favorable neurological performance, defined as a cerebral performance category (CPC) score of 2 or less at discharge. Results: In total, 523 of the 595 patients were included in the analysis. Among these, 224 survived, and 173 exhibited favorable neurological outcomes. Patients with favorable outcomes had significantly lower CFS scores than those with poor outcomes (3.2 ± 1.5 vs. 4.5 ± 1.8, Conclusions: CFS values ≤4 were independently associated with favorable neurological outcomes following OHCA.
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Registered trials
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