Evidence map›Paper›PMID 40160575›Full record

ArticleReviews in cardiovascular medicine2025

Clinical Impact of Renal Dysfunction in Patients with Severe Tricuspid Regurgitation and Chronic Heart Failure.

Beniamino Rosario Pagliaro, Pier Pasquale Leone, Alessandro Villaschi, Francesca Pugno Vanoni, Matteo Biroli, Ferdinando Loiacono, Marta Pellegrino, Giuseppe Pinto, Marta Maccallini, Matteo Pagnesi and 12 more

Abstract read
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In one paragraph

Article in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Beniamino Rosario PagliaroIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.ORCID https://orcid.org/0000-0002-1972-0986
Pier Pasquale LeoneDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Milan, Italy.
Alessandro VillaschiIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Francesca Pugno VanoniDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Milan, Italy.
Matteo BiroliDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Milan, Italy.
Ferdinando LoiaconoIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Marta PellegrinoIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Giuseppe PintoIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Marta MaccalliniIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Matteo PagnesiCardiology and Cardiac Catheterization Laboratory, ASST Spedali Civili di Brescia and Department of Medical and Surgical Specialties, University of Brescia, 25123 Brescia, Italy.
Giuliana CiminoCardiology and Cardiac Catheterization Laboratory, ASST Spedali Civili di Brescia and Department of Medical and Surgical Specialties, University of Brescia, 25123 Brescia, Italy.
Laura LupiCardiology and Cardiac Catheterization Laboratory, ASST Spedali Civili di Brescia and Department of Medical and Surgical Specialties, University of Brescia, 25123 Brescia, Italy.
Damiano Regazzoli LanciniIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Renato Maria BragatoIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Giulio StefaniniIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Bernhard ReimersIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Daniela PiniIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Marco MetraCardiology and Cardiac Catheterization Laboratory, ASST Spedali Civili di Brescia and Department of Medical and Surgical Specialties, University of Brescia, 25123 Brescia, Italy.
Gianluigi CondorelliIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Marianna AdamoCardiology and Cardiac Catheterization Laboratory, ASST Spedali Civili di Brescia and Department of Medical and Surgical Specialties, University of Brescia, 25123 Brescia, Italy.
Antonio MangieriIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
Antonio ColomboIRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Renal dysfunction (RD) is common in patients with heart failure (HF), however its impact on clinical outcomes in patients with tricuspid regurgitation (TR) and HF is still debated; therefore, we aimed to assess the impact of RD on clinical outcomes in this population. Methods: All patients with HF and a prevalent or incident diagnosis of TR presenting at two centers between January 2020 and July 2021 were enrolled, in both acute (in-hospitalized patients) and chronic settings (outpatient). Patients were stratified according to the degree of RD (Group 1 <30 mL/min (n = 70), Group 2 30-59 mL/min (n = 123) and Group 3 ≥60 mL/min (n = 56). Results: Out of 249 patients, those with severe RD had lower left ventricular ejection fraction (41.8 ± 13.1% vs. 45.7 ± 14.2% vs. 48.6 ± 13.1%, Conclusions: Severe RD is highly present in patients with HF and TR and is associated with increased incidence of all-cause mortality.

Indexed as

chronic heart failurechronic kidney diseaseright ventricular dysfunctiontricuspid regurgitation

Identifiers

PMID40160575
PMCPMC11951283

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.