Evidence map›Paper›PMID 40160424›Full record

ArticleiScience2025

Single-cell map of innate-like lymphocyte response to

G Donald Okoye, Amrendra Kumar, Farshad Ghanbari, Nowrin U Chowdhury, Lan Wu, Dawn C Newcomb, Luc Van Kaer, Holly M Scott Algood, Sebastian Joyce

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

G Donald OkoyeDepartment of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN 37232, USA.
Amrendra KumarDepartment of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN 37232, USA.
Farshad GhanbariDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Nowrin U ChowdhuryDepartment of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN 37232, USA.
Lan WuDivision of Molecular Pathogenesis, Department of Pathology, Microbiology & Immunology, Nashville, TN 37232, USA.
Dawn C NewcombDivision of Molecular Pathogenesis, Department of Pathology, Microbiology & Immunology, Nashville, TN 37232, USA.
Luc Van KaerDivision of Molecular Pathogenesis, Department of Pathology, Microbiology & Immunology, Nashville, TN 37232, USA.
Holly M Scott AlgoodDepartment of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN 37232, USA.
Sebastian JoyceDepartment of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN 37232, USA.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
VANTAGE:Consolidation to create the Vanderbilt Technologies for Advanced GenomicsG20RR030956 · NCRR · VANDERBILT UNIVERSITY · PI PIETENPOL, JENNIFER A · 2010 to 2010
$8.7M
Targeting TH17 cell metabolism in steroid resistanceR01HL136664 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NEWCOMB, DAWN C, RATHMELL, JEFFREY C. · 2017 to 2024
$4.2M
Role of autophagy-related protein Vps34 in antigen presentation and self-toleranceR01AI139046 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VAN KAER, LUC · 2019 to 2023
$2.2M
Molecular Basis of CD1D and Natural Killer T Cell FunctionR01AI137082 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JOYCE, SEBASTIAN · 2019 to 2022
$2.1M
BLRD VA I01 BX000915BLRD VA I01 BX001444BLRD VA I01 BX006010BLRD VA IK6 BX004595NCI NIH HHS P30 CA068485NCRR NIH HHS G20 RR030956NCRR NIH HHS UL1 RR024975NEI NIH HHS P30 EY008126NHLBI NIH HHS R01 HL136664NIAID NIH HHS R01 AI137082NIAID NIH HHS R01 AI139046NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

Early immune dynamics during the initiation of fatal tularemia caused by

Indexed as

Cell biologyImmunologyMicrobiology

Identifiers

PMID40160424
PMCPMC11951026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.