Evidence map›Paper›PMID 40160333›Full record

ArticleFrontiers in medicine2025

Prediction of lesion-based response to PRRT using baseline somatostatin receptor PET.

Anas Aouf, Tilman Speicher, Arne Blickle, Moritz B Bastian, Caroline Burgard, Florian Rosar, Samer Ezziddin, Amir Sabet

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anas Aouf *Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Tilman Speicher *Department of Nuclear Medicine, Saarland University Hospital, Homburg, Germany.
Arne BlickleDepartment of Nuclear Medicine, Saarland University Hospital, Homburg, Germany.
Moritz B BastianDepartment of Nuclear Medicine, Saarland University Hospital, Homburg, Germany.
Caroline BurgardDepartment of Nuclear Medicine, Saarland University Hospital, Homburg, Germany.
Florian RosarDepartment of Nuclear Medicine, Saarland University Hospital, Homburg, Germany.
Samer EzziddinDepartment of Nuclear Medicine, Saarland University Hospital, Homburg, Germany.
Amir SabetDepartment of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The heterogeneous expression of somatostatin receptors in gastroenteropancreatic neuroendocrine tumors (GEP-NET) leads to significant intra-individual variability in tracer uptake during pre-therapeutic [ Methods: A retrospective analysis was conducted on 32 patients with metastatic GEP-NET (12 pancreatic and 20 non-pancreatic), all treated with [ Results: A total of 71 lesions were included in the analysis. The mean baseline SUV Conclusion: The lesion-based molecular response to PRRT correlates with pretreatment somatostatin receptor PET uptake, particularly when expressed as tumor-to-liver SUV ratios (SUV

Indexed as

[177Lu]Lu-octreotate[68Ga]Ga-DOTATOC-PET/CTneuroendocrine tumorspeptide receptor radionuclide therapyresponse prediction

Identifiers

PMID40160333
PMCPMC11949938

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.