Evidence map›Paper›PMID 40160297›Full record

ReviewMolecular and clinical oncology2025

Treatment of advanced‑stage non‑small cell lung cancer: Current progress and a glimpse into the future (Review).

Zeming Wang, Guoying Cai, Junquan Zhu, Juchao Wang, Yufeng Zhang

Abstract readReview
In one paragraph

Review in Molecular and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Translational cancer research · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zeming WangDepartment of Integrative Medicine and Medical Oncology, Shengzhou People's Hospital (Shengzhou Branch of The First Affiliated Hospital of Zhejiang University School of Medicine, Shengzhou Hospital of Shaoxing University), Shengzhou, Zhejiang 312400, P.R. China.
Guoying CaiDepartment of Integrative Medicine and Medical Oncology, Shengzhou People's Hospital (Shengzhou Branch of The First Affiliated Hospital of Zhejiang University School of Medicine, Shengzhou Hospital of Shaoxing University), Shengzhou, Zhejiang 312400, P.R. China.
Junquan ZhuDepartment of Integrative Medicine and Medical Oncology, Shengzhou People's Hospital (Shengzhou Branch of The First Affiliated Hospital of Zhejiang University School of Medicine, Shengzhou Hospital of Shaoxing University), Shengzhou, Zhejiang 312400, P.R. China.
Juchao WangDepartment of Integrative Medicine and Medical Oncology, Shengzhou People's Hospital (Shengzhou Branch of The First Affiliated Hospital of Zhejiang University School of Medicine, Shengzhou Hospital of Shaoxing University), Shengzhou, Zhejiang 312400, P.R. China.
Yufeng ZhangDepartment of Oncology Radiotherapy, Zhuji Affiliated Hospital of Wenzhou Medical University, Zhuji, Shaoxing, Zhejiang 311800, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Before the twentieth century, patients with advanced lung cancer had limited treatment options and chemotherapy was the primary form of treatment, with an overall survival often <0.5 years. However, with advances in society and medical technology, the treatment approaches for advanced non-small cell lung cancer (NSCLC) have markedly changed. Traditional chemotherapy has been gradually replaced by targeted therapy and immunotherapy, leading to the emergence of various new therapeutic options that offer patients more personalized and precise care. This raises the question of what the future holds for the treatment of NSCLC. This review provides a comprehensive analysis of the latest breakthroughs in targeted therapies, immunotherapies, and drugs for antibody-drug conjugates (ADCs), highlights advances in multimodal combination therapy strategies, and explores the causes of resistance and the challenges that exist in overcoming it. In particular, this review provides unique insights into key directions for future research in NSCLC, such as personalised treatment strategies and biomarker exploration based on multi-omics data, aiming to provide new inspiration for clinical decision-making and research.

Indexed as

NSCLCperspectivereviewsummarizetreatment

Identifiers

PMID40160297
PMCPMC11948471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.