Evidence map›Paper›PMID 40160277›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Cut-points of the 6-min walk test, the six spot step test, and the timed-25-foot walk test discriminating impaired from non-impaired walking capacity in persons with Multiple sclerosis.

Camilla Juhl, Kasper Byskov, Lars G Hvid, Ulrik Dalgas, Uwe M Pommerich, Anders G Skjerbæk

Abstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camilla JuhlExercise Biology, Department of Public Health, Aarhus University, Denmark.ORCID https://orcid.org/0009-0000-0331-541X
Kasper ByskovExercise Biology, Department of Public Health, Aarhus University, Denmark.ORCID https://orcid.org/0009-0003-5156-3006
Lars G HvidExercise Biology, Department of Public Health, Aarhus University, Denmark.ORCID https://orcid.org/0000-0003-3233-0429
Ulrik DalgasExercise Biology, Department of Public Health, Aarhus University, Denmark.ORCID https://orcid.org/0000-0003-4132-2789
Uwe M PommerichHammel Neurorehabilitation Centre, University Research Clinic, Department of Clinical Medicine, Aarhus University, Denmark.ORCID https://orcid.org/0000-0003-1313-2056
Anders G SkjerbækExercise Biology, Department of Public Health, Aarhus University, Denmark.ORCID https://orcid.org/0000-0001-5924-2934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Assessing and interpreting walking capacity in persons with Multiple sclerosis (PwMS) is essential in clinical practice and research - and thus for PwMS themselves - yet research evaluating cut-points is limited. The present study aims to establish cut-points for 6-min walk test (6MWT), six spot step test (SSST), and timed 25-foot walk test (T25FWT) in PwMS. Methods: Classification of PwMS having walking impairments and PwMS having limited or no walking impairments was based on distinct benchmarks for each walking test, as derived from the 12-item Multiple Sclerosis Walking Scale (MSWS-12) on a 5-point Likert scale. Cut-points, area under the curve (AUC), sensitivity (Se), and specificity (Sp) were established using receiver operating characteristic curve analyses. Results: A total of Conclusion: Cut-points discriminating PwMS having walking impairments vs. PwMS having limited or no walking impairments were identified for 6MWT (446 m), SSST (8.3 s), and T25FWT (5.5 s).

Indexed as

12-items Multiple Sclerosis Walking Scale6-min walk testarea under curvecut-pointsMultiple sclerosisROC curvesix spot step testtimed 25-foot walk testwalking

Identifiers

PMID40160277
PMCPMC11951884

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.