Evidence map›Paper›PMID 40159825›Full record

ArticleClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2025

Validation of the Endoscopic Endonasal Sinus and Skull Base Surgery Questionnaire (EES-Q) for Use in Chronic Rhinosinusitis.

Marc C den Heijer, Gonneke E Joustra, Karin M Vermeulen, Astrid G W Korsten-Meijer, Robert A Feijen

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Long-term clinical control in chronic rhinosinusitis: Outcomes more than five years after surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marc C den HeijerDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-0425-613X
Gonneke E JoustraDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0001-8171-0546
Karin M VermeulenDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0001-9257-2791
Astrid G W Korsten-MeijerDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0001-5094-7698
Robert A FeijenDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-8568-0847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe Endoscopic Endonasal Sinus and Skull Base Surgery Questionnaire (EES-Q) is the only known instrument designed to assess Health-Related Quality of Life (HRQoL) in chronic rhinosinusitis (CRS) across all three health domains: physical, social, and psychological. Initially, the EES-Q was validated to evaluate the impact of endoscopic endonasal surgery (EES) on HRQoL. Our goal is to use the EES-Q for all CRS patients, regardless of their treatment phase. Previously, we demonstrated a significantly worse HRQoL in tertiary CRS patients compared to healthy individuals. The aim of this study is to validate these findings in a secondary referral cohort distributed across multiple centres, thereby extending the applicability of the EES-Q to all CRS patients.

designMulticentre know-groups validity study.

settingFive secondary referral hospitals and one tertiary referral centre.

participantsA total of 100 healthy control subjects without any history of sinusitis or current hospital-based medical treatment, 100 CRS patients from a secondary centre with no history of EES, and 100 CRS patients from a tertiary centre were included.

main outcome measuresMann-Whitney U test was performed to identify differences in domain scores and EES-Q scores between the different cohorts.

resultsThe median EES-Q scores, as well as the physical, psychological, and social domain scores, were significantly higher in the secondary and tertiary cohorts compared to the healthy controls. No significant differences were observed between the secondary and tertiary cohorts.

conclusionWe validated the EES-Q as an HRQoL instrument for use in CRS.

Indexed as

EndoscopyQuality of LifeRhinitisSinusitisSkull BaseAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedRhinosinusitisSurveys and Questionnaireschronic rhinosinusitisEES‐Qknown‐groups validitypatient‐reported outcome measurequality of life

Identifiers

PMID40159825
PMCPMC12128001

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.