Evidence map›Paper›PMID 40159723›Full record

ArticleNeurogastroenterology and motility2025

The Association of Avoidant/Restrictive Food Intake Disorder (ARFID) and Neurogastroenterology Disorders (Including Disorders of Gut-Brain Interaction [DGBI]): A Scoping Review.

Hiba Mikhael-Moussa, Valérie Bertrand, Emeline Lejeune, Claire Dupont, Alexandra Aupetit, Najate Achamrah, Chloé Melchior

Abstract readScoping Review
In one paragraph

Article in Neurogastroenterology and motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Avoidant-Restrictive Food Intake Disorder in Patients With Gastrointestinal Disorders: A Systematic Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hiba Mikhael-MoussaUniv Rouen Normandie, INSERM, Normandie Univ, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, Rouen, France.
Valérie BertrandUniv Rouen Normandie, INSERM, Normandie Univ, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, Rouen, France.
Emeline LejeuneDepartment of Digital Health, Rouen University Hospital, Rouen, France.
Claire DupontUniv Rouen Normandie, INSERM, Normandie Univ, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, Rouen, France.
Alexandra AupetitDepartment of Gastroenterology, Rouen University Hospital, Rouen, France.
Najate AchamrahUniv Rouen Normandie, INSERM, Normandie Univ, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, Rouen, France.
Chloé MelchiorUniv Rouen Normandie, INSERM, Normandie Univ, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, Rouen, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with neurogastroenterology disorders like disorders of gut-brain interaction (DGBI) and gastrointestinal (GI) motility disorders often adopt restrictive diets to manage symptoms. Without professional guidance, these patients may risk developing avoidant/restrictive food intake disorder (ARFID), potentially affecting their physical and mental health. PURPOSE: This scoping review aimed to explore the prevalence of ARFID in patients with neurogastroenterology disorders and vice versa, the direction of their association, potential risk factors, and available treatments.

methodsFollowing PRISMA-ScR guidelines, we searched PubMed, Web of Science, and Cochrane. Abstracts were screened for eligibility by two independent reviewers. KEY

resultsEighteen studies met our inclusion criteria. The prevalence of ARFID symptoms in neurogastroenterology patients ranged from 10% to 80%, while the prevalence of neurogastroenterology disorders and related GI symptoms in ARFID patients ranged from 7% to 60%. Findings on the direction of the association between eating difficulties and GI symptom occurrence were conflicting. Patients with ARFID-neurogastroenterology disorder overlap were more likely to be female, have a lower BMI, higher anxiety and depression levels, and poorer quality of life. Two small studies evaluating treatment for this overlap suggested promising effects of cognitive behavioral therapy (CBT). CONCLUSIONS AND INFERENCES: This review highlights heterogeneity in study designs and questions the suitability of ARFID assessment tools in this context. It also underscores gaps in understanding the underlying pathophysiology and treatment approaches. Future research should prioritize validating ARFID screening tools specific to this population and standardizing study methodologies. Improved understanding of this overlap will help healthcare professionals improve management strategies and patient outcomes.

Indexed as

Avoidant Restrictive Food Intake DisorderBrain-Gut AxisFeeding and Eating DisordersGastrointestinal DiseasesHumansPrevalenceARFIDavoidant restrictive food intake disorderDGBIdisorders of gut–brain interactionneurogastroenterology

Identifiers

PMID40159723
PMCPMC12351358

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.