ArticleMagnetic resonance in medicine2025
Flexible, high spatial and temporal resolution absolute thermometry of MRI phantoms using ethylene glycol.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Potential for Absolute Temperature Imaging Based on Brain Metabolites Using an FID-Shifting Approach in Gradient Echo Planar Spectroscopic Imaging (GREPSI).Magnetic resonance in medicine · 2026Article
- Flexible, high spatial and temporal resolution absolute thermometry of MRI phantoms using ethylene glycol.Magnetic resonance in medicine · 2025Article
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5 authors.
Funding
Abstract
purposeQuantitative MRI (qMRI) parameters such as relaxation rates and diffusion parameters are typically temperature dependent. Therefore, using phantoms to evaluate the accuracy of qMRI pulse sequences requires accurate knowledge of the absolute temperature throughout the phantom. This work aims to evaluate the use of ethylene glycol (EG) together with a multi-echo gradient recalled echo (ME-GRE) pulse sequence for MR spectroscopic-based measurement of absolute temperature in phantoms.
methodsWe develop and test a simple MR spectroscopic imaging approach to rapidly, automatically, accurately, and precisely measure absolute temperature at multiple locations throughout a qMRI phantom. A series of EG cubes are located throughout the phantom and imaged with a ME-GRE pulse sequence over a wide range of temperatures (˜7°C-37°C) and on multiple scanners. The resulting images were automatically processed to isolate the EG. The measured spectral peak spacing was calibrated to temperature using fiber optic probes. The accuracy and precision of the measurements were evaluated between scanners over a range of temperatures.
resultsThe spectral peak spacing of EG can be used to predict temperature with an error of 0.6°C ± 0.3°C with an increase of 0.1°C when evaluated on different scanners. An automatic reconstruction approach without manual input is described, highlighting the feasibility of online implementation on a clinical MRI scanner.
conclusionThe described MR spectroscopic imaging approach is easy to implement and provides robust, automatic, and accurate measurement of absolute temperature throughout a phantom.
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