Evidence map›Paper›PMID 40159675›Full record

ReviewMicrobiologyOpen2025

Quorum Sensing: Not Just a Bridge Between Bacteria.

Derun Liu, Yonglin Lu, Ziyun Li, Xin Pang, Xueyan Gao

Abstract readReview
In one paragraph

Review in MicrobiologyOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. The Tryptophan Biosynthesis GeneAnimals : an open access journal from MDPI · 2026
    Article
  4. Characterization of a Novel Quorum QuencherPlants (Basel, Switzerland) · 2026
    Article
  5. From screening to treatment:Microbiology spectrum · 2026
    Article
  6. Article
  7. Review
  8. Harnessing the Antimicrobial Potential of Baicalein-Coated FeACS applied materials & interfaces · 2026
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Embodied Cross-Domain Intelligence in Biomedical Microrobots: A Review.Cyborg and bionic systems (Washington, D.C.) · 2026
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Derun LiuMedical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, jinan, China.
Yonglin LuMedical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, jinan, China.
Ziyun LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.ORCID 0009-0005-1327-3168
Xin PangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Xueyan GaoMedical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, jinan, China.

Funding

This study was supported by the Natural Science Foundation of Shandong Province (ZR2022QC140) and State Key Laboratory of Microbial Technology Open Projects Fund (M2022-03).
6 · The paper itself

Abstract

The study of quorum sensing (QS) has gained critical importance, offering insights into bacterial and microorganism communication. QS, regulated by autoinducers, synchronizes collective bacterial behaviors across diverse chemical signals and target genes. This review highlights innovative approaches to regulating QS, emphasizing the potential of quorum quenching and QS inhibitors to mitigate bacterial pathogenicity. These strategies have shown promise in aquaculture and plant resistance, disrupting QS pathways to combat infections. QS also provides opportunities for developing biosensors for early disease detection and preventing biofilm formation, which is critical to overcoming antimicrobial resistance. The applications of QS extend to cancer therapy, with targeted drug delivery systems utilizing QS mechanisms. Advancements in QS regulation, such as the use of nanomaterials, hydrogels, and microplastics, provide novel methods to modulate QS systems. This review explores the latest developments in QS, recognizing its significance in controlling bacterial behavior and its broad impacts on human health and disease management. Integrating these insights into therapeutic strategies and diagnostics represents a pivotal opportunity for medical progress.

Indexed as

BacteriaBacterial Physiological PhenomenaQuorum SensingAnti-Bacterial AgentsBiofilmsBiosensing TechniquesHumansAnti-Bacterial Agentsbacterial communicationinteractionmechanismsquorum sensing

Identifiers

PMID40159675
PMCPMC11955508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.