Evidence map›Paper›PMID 40159437›Full record

ArticleCellular and molecular life sciences : CMLS2025

Dysregulated cholesterol uptake and efflux of bone marrow-derived α-SMA

Menglu Li, Lili Wu, Yuxin Wen, Anni Wang, Xiao Zhou, Lijie Ren, Qiongyu Lu, Fengchan Li, Li Zhu, Chaojun Tang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Menglu Li *Cyrus Tang Medical Institute, Soochow University, Suzhou, Jiangsu, China.
Lili Wu *Laboratories of Thrombosis and Vascular Biology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, Jiangsu, China.
Yuxin WenDepartment of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Anni WangCyrus Tang Medical Institute, Soochow University, Suzhou, Jiangsu, China.
Xiao ZhouCyrus Tang Medical Institute, Soochow University, Suzhou, Jiangsu, China.
Lijie RenCyrus Tang Medical Institute, Soochow University, Suzhou, Jiangsu, China.
Qiongyu LuCyrus Tang Medical Institute, Soochow University, Suzhou, Jiangsu, China.
Fengchan LiCyrus Tang Medical Institute, Soochow University, Suzhou, Jiangsu, China. fengcli@suda.edu.cn.
Li ZhuLaboratories of Thrombosis and Vascular Biology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, Jiangsu, China. zl15195682930@126.com.
Chaojun TangCyrus Tang Medical Institute, Soochow University, Suzhou, Jiangsu, China. zjtang@suda.edu.cn.ORCID http://orcid.org/0000-0001-8927-788X

Funding

Fellowship of China Postdoctoral Science Foundation 7121102223Natural Science Foundation of China 82070450Natural Science Foundation of China 82170466Natural Science Foundation of China 82470483Natural Science Foundation of Jiangsu Province BK20230487
6 · The paper itself

Abstract

Macrophages play differential roles in the pathogenesis of atherosclerosis due to their different phenotypes. Although α-SMA

Indexed as

ActinsCholesterolMacrophagesPlaque, AtheroscleroticAnimalsAtherosclerosisATP Binding Cassette Transporter 1Diet, High-FatMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicRAW 264.7 CellsActa2 protein, mouseActinsalpha-smooth muscle actin, mouseATP Binding Cassette Transporter 1CholesterolAtherosclerosisMacrophageOx-LDL

Identifiers

PMID40159437
PMCPMC11955436

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.