Evidence map›Paper›PMID 40159416›Full record

ArticleExperimental physiology2025

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes.

Ben J Lee, Tessa R Flood, Sophie L Russell, James J McCormick, Kelli E King, Naoto Fujii, Tatsuro Amano, Sean Notley, Glen P Kenny

Abstract read
In one paragraph

Article in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ben J LeeOccupational and Environmental Physiology Group, Centre for Physical Activity, Sport and Exercise Sciences, Coventry University, Coventry, UK.
Tessa R FloodInstitute of Sport, Manchester Metropolitan University, Manchester, UK.
Sophie L RussellOccupational and Environmental Physiology Group, Centre for Physical Activity, Sport and Exercise Sciences, Coventry University, Coventry, UK.
James J McCormickHuman and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Quebec, Canada.
Kelli E KingHuman and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Quebec, Canada.
Naoto FujiiFaculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.
Tatsuro AmanoLaboratory for Exercise and Environmental Physiology, Faculty of Education, Niigata University, Niigata, Japan.
Sean NotleyHuman and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Quebec, Canada.
Glen P KennyHuman and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Quebec, Canada.

Funding

Government of OntarioHuman and Environmental Physiology Research UnitMitacs AccelerateNatural Sciences and Engineering Research Council of Canada
6 · The paper itself

Abstract

We tested whether older adults with well-controlled type 2 diabetes or hypertension, compared with age-matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress. Twelve healthy men (age 59 years, SD 4 years), nine with type 2 diabetes (age 60 years, SD 5 years) and nine with hypertension (age 60 years, SD 4 years) walked for 180 min at 200 W/m

Indexed as

ageingcytokinesheat stresshypertensionintestinal fatty acid binding proteinlipopolysaccharide‐binding proteinplasma soluble cluster of differentiation 14type 2 diabetes

Identifiers

PMID40159416
PMCPMC13394337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.