Evidence map›Paper›PMID 40159221›Full record

ArticleCaries research2025

Mediation Effect of Dental Caries in the Relationship between Parental Locus of Control and Oral Health-Related Quality of Life.

Sharon Hui Xuan Tan, Ankur Singh, Kok Hian Tan, Johan Gunnar Eriksson, Chin-Ying Stephen Hsu

Abstract readMulticenter Study
In one paragraph

Article in Caries research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Interpretation of Standard on Clinical Dental Treatment for Children under General Anesthesia Orsedation].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sharon Hui Xuan TanSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, tan.sharon@nus.edu.sg.
Ankur SinghMelbourne School of Population and Global Health, Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia.
Kok Hian TanDuke-National University of Singapore Graduate Medical School, Singapore, Singapore.
Johan Gunnar ErikssonSingapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.
Chin-Ying Stephen HsuFaculty of Dentistry, National University of Singapore, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: The study aimed to assess the direct and indirect effect of parental locus of control (LoC) on child oral health-related quality of life.

methodsAs part of the Growing Up in Singapore towards Healthy Outcomes (GUSTO) multicenter longitudinal cohort study, sociodemographic characteristics of parents and their children were obtained at recruitment. Oral health status and dental caries outcomes were assessed at the 5th year post-natal visit and administered alongside the LoC questionnaire. Intraoral examinations were carried out by 3 trained calibrated dental professionals using the modified International Caries Detection and Assessment System (ICDAS-II) criteria. At the 6-year post-natal visit, the Early Childhood Oral Health Impact Scale (ECOHIS) was administered to mothers to assess the oral health-related quality of life (OHRQoL) of their child. Statistical analysis of the direct effects of parental LoC on OHRQoL and the causal mediation effects of dental caries were carried out using the potential outcomes approach with 1,000 simulations.

resultsA total of 312 parent-child dyads were included in this prospective cohort study. At the 5th year post-natal visit, the median decayed, missing, and filled surfaces (dmfs) was 2 (IQR 0-5), while the median LoC was 47 (IQR 43-50). The total effect of parental LoC on ECOHIS was -2.05 (95% CI: -4.03 to -0.08), of which the direct effect through dmfs was -1.45 (95% CI: -3.41 to 0.47). The percentage of the total effect of parental LoC on ECOHIS that was mediated by the presence of dental caries was 29.5% for dmfs, including incipient caries (ICDAS 1-6). The proportion mediated was lower if only active decayed surfaces were considered (23.7%) and higher if only cavitated lesions (ICDAS 3-6) (30.1%) were considered.

conclusionThe effect of parental LoC on child OHRQoL was mediated in part through the development of dental caries. </p>.

Indexed as

Dental CariesInternal-External ControlOral HealthParentsQuality of LifeAdultChildChild, PreschoolDMF IndexFemaleHumansLongitudinal StudiesMaleProspective StudiesSingaporeSurveys and QuestionnairesChildDental cariesMediation analysisPediatric dentistryPreschoolQuality of life

Identifiers

PMID40159221
PMCPMC12068828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.