Evidence map›Paper›PMID 40158846›Full record

ArticleChest2025

Bronchiectasis in Patients With Inflammatory Bowel Diseases: Prevalence, Predictors, and Clinical Characteristics.

Ophir Freund, Amir Bar-Shai, Arik Alkhazov, Dana Stav, Yitzhac Hadad, Tal Moshe Perluk, Neta Sror, Ayal Hirsch, Yulia Ron, Tamar Thurm and 4 more

Abstract read
In one paragraph

Article in Chest, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ophir FreundInstitute of Pulmonary Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel. Electronic address: ophir068@gmail.com.
Amir Bar-ShaiInstitute of Pulmonary Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Arik AlkhazovInstitute of Pulmonary Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Dana StavFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; Department of Radiology, Tel Aviv, Israel.
Yitzhac HadadFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; Department of Radiology, Tel Aviv, Israel.
Tal Moshe PerlukInstitute of Pulmonary Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Neta SrorFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Ayal HirschFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Yulia RonFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Tamar ThurmFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Amit HerlingFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Haim LeibovitzhFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Nitsan MaharshakFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Nathaniel Aviv CohenFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; IBD Unit, Department of Gastroenterology and Liver Diseases Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel diseases (IBDs) are known to be associated with bronchiectasis (BE). However, data on patients with inflammatory bowel disease-related bronchiectasis (IBD-BE) are limited. RESEARCH QUESTION: What are the prevalence, risk factors, and clinical characteristics of IBD-BE? STUDY DESIGN AND

methodsThis was a single-center retrospective study including patients who visited an IBD unit at a tertiary center between 2022 and 2023. Data on prior chest CT scans were extracted. Radiologists masked to clinical data analyzed all chest CT scans for BE. The overall prevalence of IBD-BE was estimated using multiple imputation analysis. Risk factors were analyzed in the whole cohort and after matching.

resultsA total of 1,637 patients with IBD were included, and 254 had prior chest CT scans. Of these, 30 (1.8% of the cohort) had BE. The estimated overall prevalence of IBD-BE was 5.17% (95% CI, 3.60%-8.22%). Chest cuts of available abdominal CT scans (n = 1,048) were also analyzed identifying 19 additional cases of IBD-BE, resulting in a minimal prevalence of 3%. Ulcerative colitis, prior IBD-related surgery, and extraintestinal manifestations were risk factors for IBD-BE. Of patients with chest CT scans, 63% had evidence of BE on their prior abdominal CT scans, and 70% had relevant respiratory symptoms. Despite this, most did not see a pulmonologist nor receive BE-related therapy. Clinical characteristics and outcomes were similar to patients with non-IBD-related BE.

interpretationThis study shows a relatively high prevalence of IBD-BE. The low rates of BE-directed therapy and pulmonology referral indicate the need for a higher degree of suspicion and timely referral.

Indexed as

BronchiectasisInflammatory Bowel DiseasesAdultAgedFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsTomography, X-Ray Computedchest CT scanCrohn diseaseextraintestinal manifestationspulmonary functionulcerative colitis

Identifiers

PMID40158846
PMCPMC12405926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.