Evidence map›Paper›PMID 40158203›Full record

Trial reportJournal of public health (Oxford, England)2025

Effectiveness of a theory-informed intervention to increase care home staff influenza vaccination rates: a cluster randomised controlled trial.

David Wright, Jeanette Blacklock, Veronica Bion, Linda Birt, Allan Clark, Alys Wyn Griffiths, Cecile Guillard, Susan Stirling, Andy Jones, Richard Holland and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of public health (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

David WrightSchool of Healthcare, University of Leicester, University Road, Leicester LE1 7RH, UK.
Jeanette BlacklockSchool of Healthcare, University of Leicester, University Road, Leicester LE1 7RH, UK.
Veronica BionNorwich Clinical Trials Unit, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Linda BirtSchool of Healthcare, University of Leicester, University Road, Leicester LE1 7RH, UK.
Allan ClarkNorwich Medical School, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Alys Wyn GriffithsSchool of Medicine and Population Health, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK.
Cecile GuillardNorwich Clinical Trials Unit, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Susan StirlingNorwich Clinical Trials Unit, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Andy JonesNorwich Medical School, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Richard HollandUniversity of Exeter Medical School, Heavitree Road, Exeter EX12 2LU, UK.
Liz JonesSchool of Medicine and Population Health, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK.
Thando Katangwe-ChigambaNorwich Clinical Trials Unit, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Carys SeeleyNorwich Clinical Trials Unit, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Jennifer PitcherSchool of Economics, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Helen RisebroNorwich Medical School, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Sion ScottSchool of Healthcare, University of Leicester, University Road, Leicester LE1 7RH, UK.
Adam WagnerNorwich Clinical Trials Unit, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Erika SimsNorwich Clinical Trials Unit, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.
Saiqa AhmedSchool of Medicine and Population Health, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK.
Luke CookAskham Village Community, 13 Benwick Road, March PE15 0TX, UK.
Amrish PatelSchool of Economics, University of East Anglia, Chancellors Drive, Norwich NR4 7TJ, UK.ORCID 0000-0002-2374-6409

Funding

National Institute for Health and Care Research (NIHR) Public Health Research Programme NIHR133455NIHR Applied Research Collaboration East of England at Cambridgeshire and Peterborough NHS Foundation Trust
6 · The paper itself

Abstract

backgroundCare home staff's (CHS's) influenza vaccination rate in England is 30%-40%, below the 75% WHO recommendation. We describe the effectiveness of a theory-informed and feasibility-tested intervention (in-home clinics; posters/videos to address vaccination hesitancy and care home financial incentives for uptake) to improve CHS vaccination rates.

methodRecruited care homes in England with CHS vaccination rates <40% were randomised at the home level for intervention or control. Assuming a change in CHS vaccinated from 55% to 75%, 20% attrition, and 90% power, we required 39 homes per arm. Monthly data were collected throughout flu season. The difference in vaccination rates between the arms was compared using the intention-to-treat principle and a random effect logistic regression model.

findingsThe mean % vaccination rate was 28.6% in control (n = 35) and 32.7% in intervention (n = 35) [odds ratio (OR) = 1.29, 95% confidence interval (CI): 0.68-0.4, P = .435]. In a sub-analysis, including only homes receiving at least one clinic, control was 28.6% (n = 35) and intervention was 41.7% (n = 23) (OR = 2.08, 95% CI: 0.67-2.70, P = .045).

interpretationNo effect on vaccination status was demonstrated. Within homes receiving clinics, a significant increase was observed. Process evaluation evidence suggests that starting 3 months into the influenza season partially explains this. Further evaluation initiating FluCare earlier is warranted.

Indexed as

Influenza, HumanInfluenza VaccinesNursing HomesVaccinationAgedEnglandFemaleHumansMaleMiddle AgedVaccination HesitancyInfluenza Vaccinesemployeesinfluenza vaccinationlong-term care facilitiesnursing homesresidential homessocial carestaff

Identifiers

PMID40158203
PMCPMC12123319

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.