The selection of ventilation devices in children with mild or moderate upper respiratory tract infections: a randomised controlled trial.

Jing Shi, Xiang Liu, Wenjing Chen, Wenjuan Bao

Abstract readRandomized Controlled TrialComparative Study

In one paragraph

Trial report in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Low expression of miR-126 constitutes a risk factor for perioperative respiratory adverse events among pediatric patients under general anesthesia.BMC pediatrics · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing ShiDepartment of Anesthesiology, Hebei Children's Hospital, NO.166 jianhuanan street, Shijiazhuang, Hebei, 050000, China. shij10208jing@163.com.

Xiang LiuDepartment of Anesthesiology, Hebei Children's Hospital, NO.166 jianhuanan street, Shijiazhuang, Hebei, 050000, China.

Wenjing ChenDepartment of Anesthesiology, Hebei Children's Hospital, NO.166 jianhuanan street, Shijiazhuang, Hebei, 050000, China.

Wenjuan BaoDepartment of Anesthesiology, Hebei Children's Hospital, NO.166 jianhuanan street, Shijiazhuang, Hebei, 050000, China.

Funding

Medical science research project of Hebei Province 20211805 and 20211524

6 · The paper itself

Abstract

purposeAdministering anaesthesia to children with upper respiratory tract infections (URTIs) increases the risk of perioperative respiratory adverse events (PRAEs). Several observational studies have suggested that the supraglottic airway (SGA) technique could be a potential alternative for airway management in children. This randomised controlled trial assesses whether using a SGA instead of an endotracheal tube (ETT) in children with mild or moderate URTIs affects the incidence of PRAEs.

methodsA total of 78 paediatric patients with mild or moderate URTIs who received either a SGA or ETT were included. Patients were monitored for adverse events such as cough, laryngospasm, bronchospasm, breath-holding, postoperative stridor or desaturation (< 90%) during the following stages: induction of anaesthesia, tube placement, surgery, tube removal and postanaesthesia care.

resultsThroughout the perioperative period, 56.4% (44/78) of children experienced PRAEs. The incidence was 77.5% (31/40) in those receiving ETT and 34.1% (13/38) in those receiving SGA. The relative risk (RR) of PRAEs in children receiving SGA was 0.417 (95% CI: 0.248-0.701) compared with those receiving ETT (p < 0.001). Specifically, the incidence of minor PRAEs was significantly lower in the SGA group (28.9%, 11/38) compared with the ETT group (67.5%, 27/40) (RR: 0.429, 95% CI: 0.249-0.738, p < 0.001). There were significant differences between the groups in the incidence of perioperative cough (p = 0.043) and desaturation (p = 0.031).

conclusionUsing a SGA reduced the incidence of coughing, bronchospasm and oxygen desaturation, providing an acceptable alternative to ETT in children with mild or moderate URTIs.

Indexed as

Intubation, IntratrachealRespiration, ArtificialRespiratory Tract InfectionsAge FactorsChildChild, PreschoolCoughEquipment DesignFemaleHumansInfantMaleRisk FactorsSeverity of Illness IndexTreatment OutcomeAirway managementPaediatric anaesthesiaPostanaesthesia care unitRespiratory adverse eventsUpper respiratory tract infection

Identifiers

PMID40158183

DOI10.1186/s13063-025-08815-9

PMCPMC11954290

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.