Evidence map›Paper›PMID 40158146›Full record

ArticleInternational breastfeeding journal2025

Axial spondyloarthritis and breastfeeding: a prospective study.

Emma Hortemo Grøntvedt, Ingrid Mørdre, Marianne Wallenius, Hege Svean Koksvik, Carina Gøtestam Skorpen

Abstract read
In one paragraph

Article in International breastfeeding journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emma Hortemo Grøntvedt *Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. emmahgr@stud.ntnu.no.
Ingrid Mørdre *Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Marianne WalleniusInstitute of Neuromedicine and Movement Science, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Hege Svean KoksvikDepartment of Rheumatology, Norwegian National Network for Pregnancy and Rheumatic Diseases (NKSR), St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Carina Gøtestam SkorpenDepartment of Health Sciences, Norwegian University of Science and Technology (NTNU), Ålesund, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is sparse literature on the topic of breastfeeding in women with axial spondyloarthritis (axSpA). Our aim was to obtain more knowledge about variables affecting breastfeeding for women with axSpA.

methodsThis prospective study used data from the nationwide quality register RevNatus, which collects pregnancy-related data in women with inflammatory rheumatic diseases from Norwegian outpatient clinics in rheumatology. Data were collected during January 2016 to August 2023, reporting on 436 pregnancies in 363 patients with axSpA. The study eventually included 417 births in 350 women. Breastfeeding and non-breastfeeding women were compared at six weeks, six and twelve months postpartum. We compared the groups regarding demographic and obstetric data, neonatal outcome, disease characteristics, medical treatment and self-reported data on pain, fatigue and disease burden. Information on breastfeeding was registered at least once during the follow-up postpartum. Disease activity was measured by Ankylosing Spondyloarthritis Disease Activity Index-CRP (ASDAS-CRP) and Bath Ankylosing Disease Activity Index (BASDAI).

resultsThe proportion of patients breastfeeding at the postpartum follow ups was 86% (347 women) at six weeks, 70% (221 women) at six months, and 38% (104 women) at twelve months, respectively. A larger proportion of the non-breastfeeding group had delivered with caesarean section (C-section), 24 of 59 (41%) non-breastfeeding vs 70 of 347 (20%) breastfeeding women. ASDAS-CRP was higher for the non-breastfeeding group at six weeks (2.6 vs 2.2) and at six months (2.6 vs 2.1), and BASDAI was higher for the same group at six months (4.1 vs 3.2). CRP (mg/L) was significantly higher among the non-breastfeeding at six months (5.3 vs 3.3). VAS pain scores were higher for the non-breastfeeding group at six weeks (41.0 vs 31.6) and six months (43.9 vs 31.0). VAS fatigue was higher for the same group at six months (46.8 vs 37.8).

conclusionOur results suggest that particular attention should be given regarding breastfeeding to women with active inflammatory disease and those who have undergone C-section.

Indexed as

Axial SpondyloarthritisBreast FeedingAdultFemaleHumansNorwayPostpartum PeriodPregnancyProspective StudiesAxial SpondyloarthritisBreastfeedingInflammatory rheumatic diseasesPostpartum periodProspective studyQuality of lifeRegister studyWomens health

Identifiers

PMID40158146
PMCPMC11955104

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.