ArticleJournal of health, population, and nutrition2025
The association between metabolic syndrome components and cognitive function in community-dwelling middle-aged and older adults: the first wave result of a cohort study.
Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Retarded Learning in a Rabbit Model of Metabolic Syndrome Created by Long-Term Feeding of High-Fat Diet and High Sucrose.Nutrients · 2025Article
- Clustering of Lifestyle Behaviors and Their Association With Risk of Metabolic Syndrome Among Adults in Taiwan: Nationwide Cross-Sectional Study.JMIR public health and surveillance · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundThe components of metabolic syndrome (MetS) have previously been demonstrated to be contributors to cognitive decline in older adults as individual factors, but not collectively as a syndrome. This study investigated whether adults ≥ 50 years old who meet the criteria for MetS were more likely to develop impaired cognition than those without MetS.
methodsAdults aged 50 years or older without significant cognitive impairment who received outpatient care at Taipei Veterans General Hospital were recruited. Waist circumference, blood tests for Mets components, and high-sensitivity C-reactive protein (hsCRP) were measured. Demographics, health condition, cognitive function (by Montreal Cognitive Assessment Taiwanese version, MoCA-T, and AD-8), depression symptoms (by Geriatric Depression Scale-15) and functional status (by Barthel's Index, and Lawton & Brody instrumental activities of daily living, IADL) were evaluated. Associations between MetS and cognitive function were analyzed by multivariate logistic regression.
resultsData of 567 participants were analyzed. The prevalence of MetS of the study population was 34.2%. MetS status was not significantly correlated to cognitive decline as indicated by Montreal Cognitive Assessment Taiwan version (p = 0.13) and AD-8 (p = 0.42). Mild abdominal obesity decreased the risk of developing impaired cognition in women (adjusted OR = 0.62, 95% CI = 0.42, 0.93, p = 0.02) but not in men (adjusted OR = 0.84, 95% CI = 0.46, 1.53, p = 0.58).
conclusionsMetS is not a significant contributory factor to cognitive decline in community-dwelling middle-aged and older adults. An optimal waist circumference in community-dwelling older women is protective against the development of mild dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.