SynthesisBMC public health2025
Systematic review on serotypes distribution of pneumococcal pneumonia in adults and the elderly.
Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Review
- Effects of Respiratory Vaccines in Older Adults with Cardiovascular Diseases: A Scoping Review.Vaccines · 2026Review
- Cardiovascular-Kidney-Metabolic (CKM) Syndrome as Independent Risk Factor for Pneumococcal Pneumonia: Evidence from a Territory-Wide Study.Microorganisms · 2026Article
- Article
- Erratum: Pneumococcal Vaccination of Adults in Italy: What Strategies?Journal of preventive medicine and hygiene · 2025Article
- Serotype distribution among adults with community-acquired pneumococcal pneumonia in Japan between 2019 and 2022: A multicenter observational study.Human vaccines & immunotherapeutics · 2025Observational
- Pneumococcal Vaccination of Adults in Italy: What Strategies?Journal of preventive medicine and hygiene · 2025Article
- AliC and AliD of nonencapsulatedFrontiers in cellular and infection microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPneumococcal pneumonia is a major cause of morbidity and mortality among adults, especially those over 65 years of age. Understanding pneumococcal serotype-specific epidemiology in adults and elderly is necessary to inform vaccination policies and to guide the inclusion of serotypes in pneumococcal vaccines. This study aimed to identify the serotypes causing pneumonia in the elderly.
methodsA systematic review search was performed using the PubMed database from 1984 to 2020. The search was limited to articles written in English. Studies assessing pneumococcal pneumonia in adults were included. Meta-analysis, other systematic literature reviews and case-reports were excluded. Studies published after the introduction of vaccines (PPSV23 and PCVs) were included.
resultsForty studies were included. The most common serotype identified in the majority of the articles in adults was the serotype 3 followed by serotypes 19A and 11A. Those serotypes are included in current vaccines. Emergence of non-vaccine serotypes was also observed.
conclusionPneumococcal pneumonia remains a high burden in the elderly despite the existence of vaccines for many years. In 2019, nearly 1.4 million deaths were attributable to pneumococcal pneumonia (50% of whom were over 70 years old) and was the leading cause of deaths from infectious disease worldwide. The study highlights the importance of constant monitoring serotypes emerging in this population to better target vaccination strategies.
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