SynthesisInternational journal of obesity (2005)2025
Automated lifestyle interventions and weight loss: a systematic review of randomized controlled trials.
Synthesis in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Results of the AiM, PLan, and act on LIFestYles (AMPLIFY) Weight Loss Intervention Among Survivors of Obesity-Related Cancers: A Randomized Clinical Trial.Journal of the National Comprehensive Cancer Network : JNCCN · 2026Trial
- Impact of GPT-4-Generated Discharge Letters on Patients' Medical Comprehension: Prospective Crossover Study.Journal of medical Internet research · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesOverweight and obesity drive cardiometabolic disease and high-intensity lifestyle interventions are standard. However, many health-systems cannot offer these interventions and many patients cannot participate even when available. Trials have assessed automated digital lifestyle interventions to improve accessibility. This systematic review identified automated digital lifestyle interventions and assessed their impact on weight loss. SUBJECTS/
methodsThe review (CRD42023435700) identified randomized controlled trials of at least 3-months duration assessing automated digital lifestyle interventions' impact on weight loss. Data were managed through Covidence with double-blinded screening of titles/abstracts and double-blinded full-text review to determine study inclusion. Data extraction was completed by one reviewer (NWC) and verified by a second (MM, JS, TE, CE). The Cochrane Collaboration's tool was used to assess bias risk and study quality was rated as High, Moderate, Low, or Very Low.
resultsThe search identified 1817 citations. The full-text of 60 reports were assessed and 17 reports of 16 studies were included. The majority (63%) were of moderate quality. No intervention produced 5% weight loss from baseline. Intervention components with the largest impact were text message encouragement and education with a cognitive behavioral approach. No specific form of self-monitoring was most effective, though some form of self-monitoring was included in most trials.
conclusionsSome components of the automated digital lifestyle interventions showed promise. Research is needed to optimize these components (e.g., tailored messaging, cognitive-behavioral approaches) balanced with human contact. Considering the magnitude of the problem and its disproportionate impact on low socioeconomic and minority patients, interventions optimized for effect and scalability are needed to address overweight and obesity.
Indexed as
Identifiers
40158054What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.