ArticleAnnals of nuclear medicine2025
Development and validation of a nomogram for predicting bone marrow involvement in lymphoma patients based on
Article in Annals of nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study aimed to develop and validate a nomogram combining
methodsA radiomics nomogram was developed using monocentric data, randomly divided into a training set (70%) and a test set (30%). Bone marrow biopsy (BMB) served as the gold standard for BMI diagnosis. Independent clinical risk factors were identified through univariate and multivariate logistic regression analyses to construct a clinical model. Radiomics features were extracted from PET and CT images and selected using least absolute shrinkage and selection operator (LASSO) regression, yielding a radiomics score (Rad
resultsA total of 160 patients were included, of whom 70 had BMI based on BMB results. The training group comprised 112 patients (BMI: 56, without BMI: 56), while the test group included 48 patients (BMI: 14, without BMI: 34). Independent risk factors, including the number of extranodal involvements and B symptoms, were incorporated into the clinical model. In the clinical model, CT Rad
conclusionBy integrating PET Rad
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