Observational studyBMJ open2025
Association between the preoperative triglyceride-glucose index and myocardial injury following non-cardiac surgery: a cross-sectional study.
Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Diabetes modifies the association between the triglyceride-glucose index and subclinical myocardial injury: A prospective cohort study.Cardiovascular diabetology · 2025Article
- Interaction between triglyceride-glucose-body mass index and age in coronary artery stenosis severity: a sex-stratified exploratory analysis.BMC cardiovascular disorders · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAn elevated triglyceride-glucose (TyG) index positively correlates with adverse cardiovascular events. However, its association with myocardial injury after non-cardiac surgery (MINS) remains unclear. This study aimed to examine the association between the preoperative TyG index and MINS.
designA cross-sectional study.
settingMeizhou People's Hospital.
participantsAdult patients under general anaesthesia and with MINS. MAIN EXPOSURE MEASURE: The preoperative TyG index, calculated using triglyceride (TG) and fasting blood glucose (FBG) levels.
main outcome measureThe occurrence of MINS, defined using postoperative troponin measurements.
results889 patients were included, with an 8.3% incidence of MINS (74/889). The median TyG index was 8.57 (8.13, 9.02). TyG exhibited higher discriminatory ability for MINS than TG and FBG, with an area under the curve of 0.624, 0.544 and 0.500, respectively. Fully adjusted logistic regression indicated that an elevated TyG index was independently associated with MINS (OR 1.75, 95% CI 1.21 to 2.52; p=0.003). A multivariate restricted cubic spline suggested a linear relationship between TyG and MINS (p value for non-linearity=0.059). Subgroup analyses showed results consistent with the primary analysis, with no significant interaction effects between subgroups.
conclusionAn elevated preoperative TyG index is independently associated with an increased incidence of MINS. Monitoring the TyG index perioperatively may improve the management of patients at risk for MINS. TRIAL REGISTRATION NUMBER: ChiCTR2400082834.
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