Evidence map›Paper›PMID 40157153›Full record

ArticleThe International journal on drug policy2025

The Police Opioid Seizure Temporal Risk (POSTeR) model of increased exposure to fatal overdose.

Brandon Del Pozo, Traci C Green, Morgan Godvin, Bradley Ray

Abstract read
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Article in The International journal on drug policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Brandon Del PozoThe Warren Alpert Medical School of Brown University, Rhode Island Hospital, 111 Plain Street, Providence, RI 02903, United States. Electronic address: bdelpozo@brownhealth.org.
Traci C GreenOpioid Policy Research Collaboratory, Brandies University, COBRE on Opioids and Overdose, Rhode Island Hospital, Departments of Emergency Medicine and Epidemiology, Brown Schools of Medicine and Public Health, United States.
Morgan GodvinSan Diego State University, United States.
Bradley RayRTI International, United States.

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI CURT G BECKWITH · 2018 to 2026
$23.4M
Police Diversion to Treatment for Opioid Use Disorder: A Mixed Methods StudyK01DA056654 · NIDA · RHODE ISLAND HOSPITAL · PI Brandon del Pozo · 2022 to 2026
$878k
NCIPC CDC HHS R01 CE003362NIDA NIH HHS K01 DA056654NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

contextPolice seizures of illicit opioids remain a dominant strategy for addressing problematic substance use and overdose in the United States and throughout the world, yet qualitative accounts and quantitative analyses exhibit positive associations between police opioid seizures and ensuing risk of fatal overdose at the local level of individual incidents. Since these associations run counter to the commonly held belief that removing potent illicit substances from the community is protective of overdose, a causal model is needed to demonstrate this association and convey the overdose risks that follow from police opioid seizures.

methodsLeveraging well-established biological and psychological outcomes of opioid use disorder and opioid supply interruption, our analysis presents the Police Opioid Seizure Temporal Risk (POSTeR) Model, an individual-level casual model that begins at the point of opioid dependence, introduces an interruption to an individual's supply of opioids as the result of a police drug seizure, and presents the physical and behavioral outcomes that increase the ensuing temporal risk of fatal overdose.

resultsThe aftermath of a police opioid seizure can increase a person's risk of fatal overdose. The urgent need to prevent or reduce acute opioid withdrawal symptoms leads people to seek a replacement supply, while reduced opioid tolerance resulting from post-seizure involuntary abstinence combines with the uncertain potency of a replacement supply of illicit opioids to significantly increase the difficulty of administering a safe but effective dose. In the face of these hazards, people in withdrawal often have a reduced aversion to risk, prompting them to consume this uncertain dose in a manner that increases their exposure to overdose.

conclusionsStrategies that emphasize police opioid seizures as an acceptable way to reduce the prevalence of illicit drugs in a community without accounting for the elevated risk of fatal overdose that results can worsen one of the most significant problems they are meant to address.

Indexed as

Analgesics, OpioidDrug OverdoseIllicit DrugsOpiate OverdoseOpioid-Related DisordersPoliceHumansRisk FactorsUnited StatesAnalgesics, OpioidIllicit DrugsDrug enforcementOpioidsOverdosePolicingSubstance use

Identifiers

PMID40157153
PMCPMC12045107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.