Evidence map›Paper›PMID 40156653›Full record

ArticleJournal of cancer survivorship : research and practice2025

Increased risks of type II diabetes among older Asian, Native Hawaiian, and Pacific Islander lung cancer survivors: a SEER-Medicare analysis.

Yihang Freya Zhang, Chun-Pin Esther Chang, Thomas K Varghese, Randa Tao, Mia Hashibe

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Article in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2 citing papers in PubMed.

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5 · Who and what money

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5 authors.

Yihang Freya ZhangDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
Chun-Pin Esther ChangDivision of Public Health, Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
Thomas K VargheseDivision of Cardiothoracic Surgery, Department of Surgery, University of Utah, Salt Lake City, UT, USA.
Randa TaoDepartment of Radiation Oncology, University of Utah School of Medicine, Salt Lake City, UT, USA.
Mia HashibeDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA. mhashibe@ucla.edu.

Funding

NCI NIH HHS NCI R01 CA244326
6 · The paper itself

Abstract

purposeAsian, Native Hawaiian, and Pacific Islanders (ANHPI) have a higher prevalence of type II diabetes compared to the non-Hispanic White (NHW) population. However, the incidence of type II diabetes among ANHPI lung cancer survivors is unknown. The aim of this study is to investigate the risk of newly diagnosed type II diabetes among older ANHPI lung cancer survivors compared to older NHW lung cancer survivors.

methodsWe identified 3920 ANHPI and 11,760 NHW lung cancer survivors diagnosed from 2000 to 2017 from the Surveillance, Epidemiology, and End Results (SEER)-Medicare database. Cox proportional hazard models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of type II diabetes, adjusting for potential confounding factors.

resultsOlder ANHPI lung cancer survivors had an increased risk of incident type II diabetes compared to older NHW lung cancer survivors > 1 year after cancer diagnosis. For specific ANHPI subgroups, increased risks of type II diabetes were observed among Asian Indian and Pakistani (HR, 5.14; 95% CI 2.10, 12.60) compared to NHW patients, followed by Native Hawaiian and Pacific Islander (NHPI) (HR, 4.38; 95% CI 1.22, 15.74), Vietnamese (HR, 2.32; 95% CI 1.29, 4.18), Korean (HR, 2.26; 95% CI 1.13, 4.54), Filipino (HR, 1.78; 95% CI 1.00, 3.16), and Chinese (HR, 1.75; 95% CI 1.10, 2.79) lung cancer survivors.

conclusionOlder ANHPI lung cancer survivors had a higher risk of type II diabetes compared to older NHW lung cancer survivors. Further research is needed to examine the underlying causes of health disparities in diabetes risk among ANHPI lung cancer survivors. IMPLICATIONS FOR CANCER SURVIVORS: These findings suggest that increasing surveillance on type II diabetes and monitoring body weight for older ANHPI lung cancer patients may be beneficial.

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And Pacific IslanderAsianDiabetes; Health disparitiesLung cancer survivorsNative Hawaiian

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.