Evidence map›Paper›PMID 40156584›Full record

ReviewJournal of industrial microbiology & biotechnology2024

An overview of key industrial product citric acid production by Aspergillus niger and its application.

Ambreen Latif, Noor Hassan, Hazrat Ali, Muhammad Bilal Khan Niazi, Zaib Jahan, Iqra Latif Ghuman, Farwa Hassan, Anam Saqib

Abstract readReview
In one paragraph

Review in Journal of industrial microbiology & biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Sustainable Lipid Production withMicroorganisms · 2025
    Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ambreen LatifIndustrial Biotechnology Division, National Institute for Biotechnology and Genetics Engineering-College (NIBGE-C), Pakistan Institute of Engineering & Applied Sciences (PIEAS), Faisalabad, Pakistan.ORCID 0009-0007-2894-9057
Noor HassanIndustrial Biotechnology Division, National Institute for Biotechnology and Genetics Engineering-College (NIBGE-C), Pakistan Institute of Engineering & Applied Sciences (PIEAS), Faisalabad, Pakistan.
Hazrat AliIndustrial Biotechnology Division, National Institute for Biotechnology and Genetics Engineering-College (NIBGE-C), Pakistan Institute of Engineering & Applied Sciences (PIEAS), Faisalabad, Pakistan.
Muhammad Bilal Khan NiaziSchool of Chemical & Materials Engineering, National University for Science and Technology, Islamabad, Pakistan.
Zaib JahanSchool of Chemical & Materials Engineering, National University for Science and Technology, Islamabad, Pakistan.
Iqra Latif GhumanIndustrial Biotechnology Division, National Institute for Biotechnology and Genetics Engineering-College (NIBGE-C), Pakistan Institute of Engineering & Applied Sciences (PIEAS), Faisalabad, Pakistan.
Farwa HassanIndustrial Biotechnology Division, National Institute for Biotechnology and Genetics Engineering-College (NIBGE-C), Pakistan Institute of Engineering & Applied Sciences (PIEAS), Faisalabad, Pakistan.
Anam SaqibQuinTech Center for Applied Sciences, Lahore, Pakistan.

Funding

QuinTech Center for Applied Sciences
6 · The paper itself

Abstract

Citric acid possesses high economic value and is considered as the world's largest consumed organic acid in numerous industries. Citric acid applications range from food to beverage industries, pharmaceuticals, cosmetics, and the environment. It is mostly produced by microbial fermentation, but Aspergillus niger is considered as the main workhorse for large-scale production of citric acid. In the current review, special devotion has been made toward addressing the latest and innovative literature related to production of citric acid by A. niger. The review article discusses A. niger historical involvement in citric acid production, fermentation technologies, molecular biology, biosynthesis, accumulation of citric acid, methods for enhanced production of citric acid, different operational factors also influencing citric acid production, and various techniques used for citric acid recovery. Also, copious biotechnological applications of citric acid are summarized for a fundamental comprehension of the subject and its critical role in diverse fields of industries. ONE-SENTENCE SUMMARY: This review describes the historical role of Aspergillus niger in the production of citric acid, fermentation technologies, molecular biology, techniques for increased citric acid production, and other physical and chemical variables influencing the production of citric acid.

Indexed as

Aspergillus nigerCitric AcidIndustrial MicrobiologyBiotechnologyFermentationCitric AcidA. nigerCitric acidFermentationIndustryMolecular biology

Identifiers

PMID40156584
PMCPMC11956825

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.