SynthesisAsian Pacific journal of cancer prevention : APJCP2025
Role of SNHGs in Adverse Prognostic Factors in Cervical Cancer: A Systematic Review.
Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- SNHG26 Promotes Colorectal Cancer Progression via CDKN2A-Dependent Regulation of Cuproptosis and CD8+ T Cell-Mediated Immunity.Journal of cellular and molecular medicine · 2025Article
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11 authors.
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Abstract
objectiveThis study aims to summarize the main findings in the literature regarding the family of long non-coding RNAs (LncRNAs), specifically SNHGs, in cervical cancer.
methodsThe study was conducted following the PRISMA protocol, using the PICOS framework for the search strategy. The research sources included PubMed, ScienceDirect, Lilacs, and Medline. Inclusion and exclusion criteria were applied, and data from each article were extracted, including: clinicopathological characteristics, biological function of SNHGs, clinical indicators, and diagnostic and prognostic markers.
resultsOut of a total of 3.803 studies, 12 were selected, encompassing 8 SNHGs (GAS5, SNHG5, SNHG7, SNHG12, SNHG14, SNHG16, SNHG17, and SNHG20) associated with cervical cancer. All, except for GAS5, showed increased expression. In the literature review, SNHG expression was linked to adverse prognostic factors in cervical cancer, such as proliferation, migration, invasion, lymph node metastasis, and apoptosis.
conclusionAlthough further studies are needed, these data highlight the significant role of SNHGs in tumor biology and the promising potential of this class of transcripts as tools in the clinical management of cervical cancer.
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