Evidence map›Paper›PMID 40156260›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Improvements in endovascular stroke treatment workflow over 5 years: ESCAPE to ESCAPE-NA1.

Johanna M Ospel, Mayank Goyal, Ryan McTaggart, Alexandre Y Poppe, Andrew M Demchuk, J Rempel, J Thornton, Ricardo A Hanel, Mohammed Almekhlafi, Bruce Cv Campbell and 10 more

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Johanna M OspelDepartment of Diagnostic Imaging, University of Calgary, Calgary, AB Canada.ORCID 0000-0003-0029-6764
Mayank GoyalDepartment of Diagnostic Imaging, University of Calgary, Calgary, AB Canada.ORCID 0000-0001-9060-2109
Ryan McTaggartWarren Alpert School of Medicine, Brown University, Providence, RI, USA.
Alexandre Y PoppeDepartment of Neurology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Andrew M DemchukDepartment of Clinical Neurosciences, University of Calgary, Calgary, AB Canada.
J Rempel
J ThorntonDepartment of Neuroradiology, Beaumont Hospital, Dublin, Ireland.
Ricardo A HanelLyerly Neurosurgery, Baptist Hospital, Jacksonville, FL, USA.
Mohammed AlmekhlafiDepartment of Clinical Neurosciences, University of Calgary, Calgary, AB Canada.
Bruce Cv CampbellThe Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, Australia.
René ChapotDepartment of Neuroradiology, Alfried Krupp Krankenhaus, Essen, Germany.
Diogo HaussenEmory University School of Medicine, Grady Memorial Hospital, Atlanta, GA, USA.
Mahesh JayaramanWarren Alpert School of Medicine, Brown University, Providence, RI, USA.
Joung-Ho RhaDepartment of Neurology, Inha University Hospital Neurology, Incheon, South Korea.
Richard H SwartzDepartment of Neurology, Sunnybrook Health Sciences Centre, Toronto, Canada.
Michael TymianskiNoNO Inc., Toronto, Canada.
Bijoy K MenonDepartment of Clinical Neurosciences, University of Calgary, Calgary, AB Canada.
Raul G NogueiraDepartment of Neurology, University of Pittsburgh Medical Centre, Pittsburgh, USA.
Michael D HillDepartment of Diagnostic Imaging, University of Calgary, Calgary, AB Canada.
ESCAPE and ESCAPE-NA1 investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and PurposeRapid treatment is a major determinant of outcome in acute ischemic stroke patients with large vessel occlusion. We used patient-level data from the ESCAPE and ESCAPE-NA1 trials to evaluate whether and to what extent workflow interval times have improved over time.MethodsData were derived from the ESCAPE and the ESCAPE-NA1 randomized trials. Workflow interval times and reperfusion quality were summarized using descriptive statistics and compared on a patient level between the two trials using the Wilcoxon rank sum test and Fisher's exact test. The effect of patient baseline characteristics, including patient age, sex and stroke severity as measured by the National Institutes of Health Stroke Scale, on workflow times was determined using linear regression.ResultsAll patients from the ESCAPE trial (

Indexed as

acute ischemic strokelarge vessel occlusion strokeStrokesystems of carethrombectomy

Identifiers

PMID40156260
PMCPMC11955977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.