Evidence map›Paper›PMID 40155957›Full record

ArticleHead & face medicine2025

Predicting changes of incisor and facial profile following orthodontic treatment: a machine learning approach.

Jing Peng, Yan Zhang, Mengyu Zheng, Yanyan Wu, Guizhen Deng, Jun Lyu, Jianming Chen

Abstract read
In one paragraph

Article in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing PengDepartment of Orthodontics, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China.
Yan ZhangDepartment of Orthodontics, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China.
Mengyu ZhengDepartment of Orthodontics, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China.
Yanyan WuDepartment of Orthodontics, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China.
Guizhen DengDepartment of Stomatology, LianZhou People's Hospital, Qingyuan, China.
Jun Lyu *Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China. lyujun2020@jnu.edu.cn.ORCID https://orcid.org/0000-0002-2237-8771
Jianming Chen *Department of Orthodontics, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China. orangeforest393@163.com.ORCID https://orcid.org/0000-0001-8753-8943

Funding

The General Guiding Project of Guangzhou Municipal Health Commission 20241A011096The study was supported by Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization 2021B1212040007
6 · The paper itself

Abstract

backgroundFacial aesthetics is one of major motivations for seeking orthodontic treatment. However, even for experienced professionals, the impact and extent of incisor and soft tissue changes remain largely empirical. With the application of interdisciplinary approach, we aim to predict the changes of incisor and profile, while identifying significant predictors.

methodsA three-layer back-propagation artificial neural network model (BP-ANN) was constructed to predict incisor and profile changes of 346 patients, they were randomly divided into training, validation and testing cohort in the ratio of 7:1.5:1.5. The input data comprised of 28 predictors (model measurements, cephalometric analysis and other relevant information). Changes of U1-SN, LI-MP, Z angle and facial convex angle were set as continuous outcomes, mean square error (MSE), mean absolute error (MAE) and coefficient of determination (R²) were used as evaluation index. Change trends of Z angle and facial convex angle were set as categorical outcomes, accuracy, precision, recall, and F1 score were used as evaluation index. Furthermore, we utilized SHapley Additive exPlanations (SHAP) method to identify significant predictors in each model.

resultsMSE/MAE/R

conclusionBP-ANN could be a promising method for objectively predicting incisor and profile changes prior to orthodontic treatment. Such model combined with key influential predictors could provide valuable reference for decision-making process and personalized aesthetic predictions.

Indexed as

Esthetics, DentalFaceIncisorMachine LearningOrthodontics, CorrectiveAdolescentCephalometryFemaleHumansMaleNeural Networks, ComputerYoung AdultArtificial neural networkIncisor predictionOrthodontic treatmentProfile predictionSHapley additive exPlanations

Identifiers

PMID40155957
PMCPMC11951650

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.