Evidence map›Paper›PMID 40155853›Full record

ArticleBMC psychiatry2025

A national survey of suicidality and non-suicidal self-injury in bipolar disorder: insights from network analysis.

Lvchun Cui, Yuncheng Zhu, Yang Li, Jia Zhou, Guiyun Xu, Miao Pan, Zhiyu Chen, Wenfei Li, Zhian Jiao, Mingli Li and 21 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Lvchun Cui *Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, No. 600 Wanping South Road, Shanghai, 200030, China.
Yuncheng Zhu *Clinical Research Center for Mental Health, Mental Health Center Affiliated to School of Medicine, Shanghai University, Shanghai, China.
Yang LiBeijing Anding Hospital, Capital Medical University, Beijing, China.
Jia ZhouBeijing Anding Hospital, Capital Medical University, Beijing, China.
Guiyun XuAffiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Miao PanSecond Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China.
Zhiyu ChenHangzhou Seventh People's Hospital, Hangzhou, Zhejiang, China.
Wenfei LiAnhui Mental Health Center, Hefei, Anhui, China.
Zhian JiaoShandong Provincial Hospital, Jinan, Shandong, China.
Mingli LiWest China Hospital of Sichuan University, Chengdu, Sichuan, China.
Yong ZhangTianjin Anding Hospital, Tianjin, China.
Jingxu ChenBeijing Huilongguan Hospital, Beijing, China.
Xiuzhe ChenShandong Mental Health Center, Jinan, Shandong, China.
Na LiFirst Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Jing SunNanjing Brain Hospital, Nanjing, Jiangsu, China.
Jian ZhangShenzhen Kangning Hospital, Shenzhen, Guangdong, China.
Shaohua HuFirst Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Haishan WuThe Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Zhaoyu GanNo. 3 Hospital of Zhongshan University, Guangzhou, Guangdong, China.
Yan QinDalian Seventh People's Hospital, Dalian, Liaoning, China.
Yumei WangThe First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yantao MaPeking University Institute of Mental Health, Beijing, China.
Xiaoping WangThe Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Xiaohong LiBeijing Anding Hospital, Capital Medical University, Beijing, China.
Chuangxin WuShanghai Hongkou Mental Health Center, No.159 Tongxin Road, Shanghai, 200083, China.
Yiyun CaiShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, No. 600 Wanping South Road, Shanghai, 200030, China.
Jiaye ChenShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, No. 600 Wanping South Road, Shanghai, 200030, China.
Baichuan WuShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, No. 600 Wanping South Road, Shanghai, 200030, China.
Zuowei WangClinical Research Center for Mental Health, Mental Health Center Affiliated to School of Medicine, Shanghai University, Shanghai, China. wzwhk@163.com.
Daihui PengShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, No. 600 Wanping South Road, Shanghai, 200030, China. pdhsh@126.com.
Yiru FangShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, No. 600 Wanping South Road, Shanghai, 200030, China. yirufang@aliyun.com.

Funding

Capability Promotion Project for Research-oriented Doctor at Shanghai Mental Health Center 2021-YJXYS-02Excellent Talent Training Program of Shanghai Hongkou Mental Health Center 2023XKDTR01Fundamental Research Funds for the Central Universities YG2023QNA45Health System Key Discipline of Shanghai 2024ZDXK0013Scientific Research Project of Hongkou District Health Commission 2401-06Shanghai Clinical Research Center for Mental Health SCRC-MH, 19MC1911100Shanghai Key Medicine Specialties Program ZK2019A06Shanghai Sailing Program 23YF1437900STI2030-Major Projects 2021ZD0200602
6 · The paper itself

Abstract

backgroundThere is a high prevalence of suicidal ideation (SI), suicide attempts (SA), and non-suicidal self-injury (NSSI) in bipolar disorder (BD). Understanding the nature of suicidality and NSSI in BD is an important way to inform optimal intervention for reducing suicide risk. We aimed to investigate the prevalence and correlates of SI, SA, and NSSI in patients with BD using data from a national survey. We used network analysis to explore the associations among suicidality, NSSI, addictive features of NSSI, and symptoms of BD.

methodsParticipants with BD were recruited from 20 research centers in China. Suicidality, NSSI, addictive features, and symptoms of BD were measured via a standardized electronic case report form. We used logistic regression and network analysis for data analysis.

resultsOf the 1,055 participants recruited, over 50% with depressive or mixed episodes had SI, more than 20% engaged in SA, and over 40% reported NSSI. The polarity of mood episodes was independently associated with SI ([hypo]mania vs. mixed episodes: odds ratio [OR] = 0.22, 95% confidence interval [CI] 0.14-0.33, p < 0.001) and NSSI ([hypo]mania vs. mixed episodes: OR = 0.33, 95% CI 0.19-0.58, p < 0.001; depressive episodes vs. mixed episodes: OR = 0.59, 95% CI 0.35-0.98, p = 0.040). Participants with mixed episodes reported the most severe addictive features of NSSI. SI was the most influential symptom within the network model of the total sample; NSSI, SI, and depressive symptoms were identified as key "bridge symptoms".

conclusionsSuicidality and NSSI in BD were closely associated with depressive and mixed episodes, with mixed episodes showing the highest prevalence of NSSI and the most pronounced addictive features. SI was identified as the central symptom within the self-harm network, emphasizing its importance as an intervention target. These findings could offer potential insights regarding suicidality and NSSI in BD that can inform intervention strategies.

Indexed as

Bipolar DisorderSelf-Injurious BehaviorSuicidal IdeationSuicide, AttemptedAdultChinaFemaleHumansMaleMiddle AgedPrevalenceYoung AdultAddictive featuresBipolar disorderNetwork analysisNon-suicidal self-injurySuicide

Identifiers

PMID40155853
PMCPMC11951841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.