Evidence map›Paper›PMID 40155842›Full record

ArticleBMC public health2025

Hemoglobin as a mediator between air pollution and growth outcomes in children under 60 months: the moderating role of nutritional supplementation.

Xingyi Jin, Di Wu, Fei Ge, Dan Cui, Ayidana Jumabieke, Xiaoli Wang, Rui Wang, Niannian Wang, Jihan Sun, Wang Liao and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Environmental Stressors, Anemia, and Depressive Symptoms in Pregnancy: Unpacking the Combined Risks.International journal of environmental research and public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xingyi JinKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Di WuDepartment of Gynaecology and Obstetrics, Zhongda Hospital, Southeast University, Nanjing, China.
Fei GeMaternal and Child Health Hospital of Xinjiang Uygur Autonomous Region, Wulumuqi, China.
Dan CuiMaternal and Child Health Hospital of Xinjiang Uygur Autonomous Region, Wulumuqi, China.
Ayidana JumabiekeMaternal and Child Health Hospital of Xinjiang Uygur Autonomous Region, Wulumuqi, China.
Xiaoli WangKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Rui WangKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Niannian WangKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Jihan SunKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Wang LiaoKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Da PanKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Li ShaoClinical Medical Research Center for Plateau Gastroenterological Disease of Xizang Autonomous Region, School of Medicine, Xizang Minzu University, Xianyang, 712082, China.
Shaokang WangKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China. shaokangwang@seu.edu.cn.
Chunyan YuanDepartment of Gynaecology and Obstetrics, Zhongda Hospital, Southeast University, Nanjing, China. ycy720119@163.com.
Guiju SunKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.

Funding

Autonomous Region Health Youth Medical Science and Technology Talent Project WJWY-202457Chinese Association for Improving Birth Outcome and Child Development 2024K036National center for women and children's health, NHC, PRC 2024FYH24Postgraduate Research &Practice Innovation Program of Jiangsu Province KYCX24_0487SEU Innovation Capability Enhancement Plan for Doctoral Students CXJH_SEU 24213
6 · The paper itself

Abstract

backgroundPrior research has yielded incongruent results about the association between air pollutants and offspring hemoglobin levels, as well as between air pollutants and child development. This may be because previous studies have not taken both air pollution and nutrition into account. This study sought to examine the correlations between postnatal exposure to air pollution (PM

methodsA unified nutrition package intervention study was conducted in western, China between 2016 and 2023. In accordance with WHO guidelines, stunting, underweight, height-for-age z score (HFA), weight-for-age z score (WFA), and anemia status were all defined. A daily average of PM

findingsThis study examined the impact of postnatal air pollution exposure on child growth, mediated by hemoglobin levels and moderated by nutritional supplementation (YingYangBao, YYB). Our findings suggest that air pollution negatively affects growth via reduced hemoglobin levels, but extended nutritional supplementation mitigates this effect. A total of 10,766 children under 5 years of age participated in this study. All four air pollutants were associated with reduced hemoglobin levels, but their effects on growth and development were not uniform. Specifically, PM

conclusionPostnatal exposure to air pollution (PM

Indexed as

Air PollutionChild DevelopmentDietary SupplementsEnvironmental ExposureHemoglobinsAir PollutantsChild, PreschoolChinaFemaleGrowth DisordersHumansInfantMaleParticulate MatterAir PollutantsHemoglobinsParticulate MatterAir pollutionHemoglobin levelsNutrition interventionStuntingUnderweight

Identifiers

PMID40155842
PMCPMC11954182

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.