Evidence map›Paper›PMID 40155680›Full record

ArticleScientific reports2025

Fine-tuned deep learning models for early detection and classification of kidney conditions in CT imaging.

Amit Pimpalkar, Dilip Kumar Jang Bahadur Saini, Nilesh Shelke, Arun Balodi, Gauri Rapate, Manoj Tolani

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amit PimpalkarSchool of Computer Science and Engineering, Ramdeobaba College of Engineering and Management, Ramdeobaba University, Nagpur, Maharashtra, India.
Dilip Kumar Jang Bahadur SainiDepartment of Computer Science and Engineering (Cyber Security), School of Engineering, Dayananda Sagar University, Bangalore, India.
Nilesh ShelkeSymbiosis Institute of Technology, Nagpur Campus, Symbiosis International (Deemed University), Pune, India.
Arun BalodiDepartment of Electronics and Communication Engineering, Dayananda Sagar University, Bengaluru, Karnataka, India.
Gauri RapatePES University, Bangalore, Karnataka, India.
Manoj TolaniDepartment of Information and Communication Technology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, India. manoj.tolani@manipal.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The kidney plays a vital role in maintaining homeostasis, but lifestyle factors and diseases can lead to kidney failures. Early detection of kidney disease is crucial for effective intervention, often challenging due to unnoticeable symptoms in the initial stages. Computed tomography (CT) imaging aids specialists in detecting various kidney conditions. The research focuses on classifying CT images of cysts, normal states, stones, and tumors using a hyperparameter fine-tuned approach with convolutional neural networks (CNNs), VGG16, ResNet50, CNNAlexnet, and InceptionV3 transfer learning models. It introduces an innovative methodology that integrates finely tuned transfer learning, advanced image processing, and hyperparameter optimization to enhance the accuracy of kidney tumor classification. By applying these sophisticated techniques, the study aims to significantly improve diagnostic precision and reliability in identifying various kidney conditions, ultimately contributing to better patient outcomes in medical imaging. The methodology implements image-processing techniques to enhance classification accuracy. Feature maps are derived through data normalization and augmentation (zoom, rotation, shear, brightness adjustment, horizontal/vertical flip). Watershed segmentation and Otsu's binarization thresholding further refine the feature maps, which are optimized and combined using the relief method. Wide neural network classifiers are employed, achieving the highest accuracy of 99.96% across models. This performance positions the proposed approach as a high-performance solution for automatic and accurate kidney CT image classification, significantly advancing medical imaging and diagnostics. The research addresses the pressing need for early kidney disease detection using an innovative methodology, highlighting the proposed approach's capability to enhance medical imaging and diagnostic capabilities.

Indexed as

Deep LearningImage Processing, Computer-AssistedKidneyKidney DiseasesTomography, X-Ray ComputedEarly DiagnosisHumansNeural Networks, ComputerComputed tomography scansDistance transformHyperparameter-fine-tuningKidney disease classificationOtsu’s binarizationTransfer learningWatershed segmentation

Identifiers

PMID40155680
PMCPMC11953426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.