Evidence map›Paper›PMID 40155675›Full record

ArticleScientific reports2025

Deciphering the tumor-suppressive role of RBMS3 in lung adenocarcinoma through genomic insights into prognosis and mechanisms.

Li Lv, Tengxiang Zhong, Zhenkun Li, Wenhui Zhang, Yi Zhang, Ying Liang, Rongqing Li, Mingxia Ding, Jie Lin

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Frontiers in molecular biosciences · 2026
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li LvDepartment of Medical Oncology, The Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, 650101, Yunnan, China.
Tengxiang ZhongGuangxi Medical University, Nanning City, China.
Zhenkun LiDepartment of Medical Oncology, The Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, 650101, Yunnan, China.
Wenhui ZhangDepartment of Medical Oncology, The Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, 650101, Yunnan, China.
Yi ZhangDepartment of Thyroid - Breast Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Ying LiangDepartment of Thyroid - Breast Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Rongqing LiDepartment of Radiation Oncology, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Wuhua District, Kunming, 650032, Yunnan, China. lrqmxl@126.com.
Mingxia DingDepartment of Medical Oncology, The Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, 650101, Yunnan, China. dmx7166@126.com.
Jie LinDepartment of Medical Oncology, The Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, 650101, Yunnan, China. linjie@kmmu.edu.cn.

Funding

2023 Talent Training Project of the Second Affiliated Hospital of Kunming Medical University RCTDHB-2023062023 Talent Training Project of the Second Affiliated Hospital of Kunming Medical University RCTDXK-202304the National Natural Science Foundation of China 82160453the Yunnan Province Science and Technology Planning Project 202101AY070001-143
6 · The paper itself

Abstract

Lung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality, underscoring the urgent need for novel biomarkers and therapeutic targets. Through transcriptomic analysis of 4456 genes in TCGA-LUAD cohorts, we identified RBMS3 as a significantly downregulated tumor suppressor (log

Indexed as

Adenocarcinoma of LungGene Expression Regulation, NeoplasticLung NeoplasmsRNA-Binding ProteinsA549 CellsCell CycleDatabases, FactualGene Expression ProfilingGenes, Tumor SuppressorHumansKaplan-Meier EstimateLymphocytesNeoplasm InvasivenessNeutrophilsTrans-ActivatorsTranscriptomeRBMS3 protein, humanRNA-Binding ProteinsTrans-ActivatorsDifferentially expressed genesLung adenocarcinomaPrognosisRBMS3Risk score model

Identifiers

PMID40155675
PMCPMC11953446

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.