Evidence map›Paper›PMID 40155660›Full record

ArticleScientific reports2025

Decrease in atmospheric pressure could increase endolymphatic space volume in Meniere's disease.

Masaharu Sakagami, Tadashi Kitahara, Tadao Okayasu, Tomoyuki Shiozaki, Hiroto Fujita, Keita Ueda, Hajime Kageyama, Hiroshi Inui

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Masaharu SakagamiDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan. m.sakagami@naramed-u.ac.jp.
Tadashi KitaharaDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Tadao OkayasuDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Tomoyuki ShiozakiDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Hiroto FujitaDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Keita UedaDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Hajime KageyamaDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Hiroshi InuiDepartment of Otolaryngology- Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with Meniere's disease (MD) often suffer from vertiginous symptoms during bad weather. Endolymphatic hydrops (EH) have been thought to be the pathological basis of MD. However, the relationship between EH and weather has not been clarified. Endolymphatic space (ELS) volume can be evaluated using three-dimensional analysis of 3-Tesla magnetic resonance imaging (3T-MRI) after intravenous injection of gadolinium enhancement. In this study, we examined the correlations between the 24-h atmospheric pressure change from the day before, that is, MRI scanning, and the ELS rates of the unilateral MD (uMD) and patients with chronic rhinosinusitis as a control group. Atmospheric pressure data for the day before and on the day of each patient's MRI were obtained from the Japan Meteorological Agency data (JMA). There was no significant correlation between the atmospheric pressure change and the ELS rate on the affected and healthy sides or bilaterally in the control group. However, in those with developed MD (average hearing levels in the affected ear of 40-70 dB), a significant negative correlation was found between atmospheric pressure change and vestibular ELS rate on the affected side. Negative atmospheric pressure changes may influence vestibular ELS volume in patients with moderate hearing impairment.

Indexed as

Atmospheric PressureMeniere DiseaseAdultAgedCase-Control StudiesEndolymphatic HydropsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedAtmospheric pressureEndolymphatic hydropsGadoliniumInner ear MRIMeniere’s diseaseWeather

Identifiers

PMID40155660
PMCPMC11953306

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