Evidence map›Paper›PMID 40155645›Full record

ArticleTranslational psychiatry2025

Network analysis of central symptoms in Chinese young adults with subthreshold depression.

Xiumin Jiang, Xiaotong Wang, Lin Yu, Jun He, Shengwei Wu, Yuanyuan Zhou, Meng Zhang, Lin Yao, Jinglan Yan, Yuanjia Zheng and 1 more

Abstract read
In one paragraph

Article in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiumin Jiang *Institute of acupuncture and moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID http://orcid.org/0009-0002-7081-2488
Xiaotong Wang *School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China.ORCID http://orcid.org/0000-0002-5329-2663
Lin YuDepartment of Traditional Chinese Medicine, the Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.
Jun HeRehabilitation Center, Counseling Department, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Shengwei WuDepartment of Traditional Chinese Medicine, the Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.
Yuanyuan ZhouInstitute of acupuncture and moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China.
Meng ZhangInstitute of acupuncture and moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China.
Lin YaoInstitute of acupuncture and moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China.
Jinglan YanInstitute of acupuncture and moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China.
Yuanjia ZhengInstitute of acupuncture and moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China.
Yongjun ChenInstitute of acupuncture and moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China. chenyongjun@sdutcm.edu.cn.ORCID http://orcid.org/0000-0003-4614-7836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subthreshold depression (SD) is a prevalent condition among young adults, significantly increasing the risk of developing major depressive disorder (MDD). While the symptoms of MDD are well-documented, the network structure and key symptoms of SD, which forms a complex, interdependent system, have not been fully elucidated. This study sought to identify the central symptoms and their interconnections within the depressive symptom network in young adults with SD. A total of 834 Chinese young adults with SD completed the 21-item Beck Depression Inventory 2nd version (BDI-II) and were included in this study. Network analysis was employed to identify central symptoms (nodes) and associations between symptoms (edges) as assessed by the BDI-II. Additionally, centrality indicators for network robustness underwent assessment through stability and accuracy tests. The analysis revealed that Loss of interest was the most central node in the SD symptom network, with Tiredness/fatigue and Agitation following closely. Significant associations were observed between Loss of energy and Concentration difficulties, Agitation and Irritability, Guilty feelings and Self-dislike, as well as Tiredness and Loss of pleasure. The network demonstrated robustness across stability and accuracy assessments. Loss of interest, Tiredness/fatigue, and Agitation were pivotal symptoms within the depressive symptom network of SD in young adults. These symptoms may serve as critical targets for therapeutic interventions and should be prioritized in future psychological and neurobiological research to advance our understanding of SD.

Indexed as

DepressionAdolescentAdultChinaEast Asian PeopleFatigueFemaleHumansMalePsychiatric Status Rating ScalesYoung Adult

Identifiers

PMID40155645
PMCPMC11953349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.