Evidence map›Paper›PMID 40155473›Full record

ArticleCommunications biology2025

Defining gastric cancer ecology: the crucial roles of TREM2

Qianqian Cao, Dianshui Sun, Can Tu, Jihua Wang, Runjia Fu, Rumei Gong, Yueying Xiao, Qin Liu, Xiaomei Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qianqian CaoCancer Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Dianshui SunCancer Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Can TuVascular Intervention Department, The First Affiliated Hospital of Ningbo University, Ningbo, PR China.
Jihua WangCancer Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Runjia FuCancer Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Rumei GongCancer Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Yueying XiaoDepartment of Spine Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Qin LiuCancer Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Xiaomei LiTumor Research and Therapy Center, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, PR China. xugongwen@sdu.edu.cn.ORCID http://orcid.org/0009-0008-5945-0395

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) remains a major global health challenge, characterized by a complex tumor microenvironment (TME) that significantly influences disease progression and therapeutic outcomes. This study focuses on TREM2

Indexed as

Cancer-Associated FibroblastsMacrophagesMembrane GlycoproteinsReceptors, ImmunologicStomach NeoplasmsTumor MicroenvironmentAnimalsCell Line, TumorCell ProliferationChemokine CXCL12HumansMiceReceptors, CXCR4Signal TransductionChemokine CXCL12CXCL12 protein, humanCXCR4 protein, humanMembrane GlycoproteinsReceptors, CXCR4Receptors, ImmunologicTREM2 protein, human

Identifiers

PMID40155473
PMCPMC11953254

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.