ArticleNature communications2025
Fertilization-induced synergid cell death by RALF12-triggered ROS production and ethylene signaling.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- OsRALF26 Serves as an Endogenous Signal Recognised by XA21 to Promote Robust and Distal Resistance in Rice.Plant biotechnology journal · 2026Article
- Basis of apomixis in flowering plants - state of the art and research perspectives.Plant reproduction · 2026Review
- Comparing In Vivo and In Vitro Pollen Tube Attraction Assays for Arabidopsis and Maize.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Genotype-dependent induction of embryogenic callus and programmed cell death in Korean pine.BMC plant biology · 2025Article
- Small signaling peptides define leaf longevity.Frontiers in plant science · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Fertilization-dependent elimination of the persistent synergid cell is essential to block supernumerary pollen tubes and thus to avoid polyspermy in flowering plants. Little is known about the molecular mechanisms ensuring timely induction and execution of synergid cell death. We analyzed manually isolated maize synergid cells along their degeneration and show that they are gland cells expressing batteries of genes encoding small secreted proteins under control of the MYB98 transcription factor. This network is down-regulated after fertilization, while genes involved in reactive oxygen species (ROS) production, ethylene biosynthesis and response, senescence, and oxidative stress regulation are induced before synergid elimination and its ultimate fusion with the endosperm. We further show that the fertilization-induced RALF12 peptide specifically triggers mitochondrial ROS and apoptosis, while ethylene promotes synergid degeneration. In conclusion, this study sheds light on developmental programmed cell death (dPCD) in plants and provides a unique resource to discover unknown PCD regulators.
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Registered trials
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