Evidence map›Paper›PMID 40155347›Full record

ArticlePsycho-oncology2025

Living Well With Uncertainty in Advanced, Metastatic or Incurable Cancers: A Pragmatic Feasibility Study of the Adapting to Life With Cancer Cognitive ExisteNtial Therapy (ACCENT).

Cheryl Harris, Lauriane Giguère, Alanna Chu, Jani Lamarche, Tori Langmuir, Kerry Menelas, Nicole Rutkowski, Ghizlène Sehabi, Sophie Lebel

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Article in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cheryl HarrisNeuroscience Program, The Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Canada.
Lauriane GiguèreSchool of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, Canada.ORCID 0000-0002-6992-3132
Alanna ChuSchool of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, Canada.
Jani LamarcheSchool of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, Canada.ORCID 0000-0002-9501-4135
Tori LangmuirNeuroscience Program, The Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Canada.
Kerry MenelasSchool of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, Canada.
Nicole RutkowskiSchool of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, Canada.
Ghizlène SehabiSchool of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, Canada.
Sophie LebelSchool of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNew treatments are contributing to individuals living longer with advanced, metastatic, or incurable (AMI) cancers. The impact of these treatments is unpredictable, resulting in considerable uncertainty for these patients. Currently, there are no interventions that effectively address uncertainty in AMI cancers. To fill this gap, we designed the Adapting to life with Cancer Cognitive ExisteNtial Therapy (ACCENT) intervention.

aimTo evaluate the feasibility, acceptability, and preliminary efficacy of ACCENT in AMI cancers.

methodsACCENT was delivered online for 6 consecutive weekly sessions of 1.5 hours to five groups of six to seven patients. Thirty-two patients were interested in participating, but 2 did not complete the assessments pre- or post-intervention. A pragmatic feasibility study was conducted using data collected in routine clinical practice. Participants completed the Intolerance of Uncertainty Scale-Short Form, the Generalized Anxiety Disorder scale, and the Impact of Events Scale before and after the intervention. Post-intervention, participants answered open-ended questions to assess acceptability, rated their perceptions of improvement and usefulness, and completed the Satisfaction with Therapy and Therapist Scale.

resultsACCENT appears feasible with participants completing the intervention and all assessments between January 2022 and November 2023. It appears acceptable with an attrition rate of 12.5%, and a high degree of attendance and satisfaction. There was a non-significant decrease in intolerance of uncertainty, and a significant decrease in anxiety, and cancer-specific distress post-intervention.

conclusionA randomized controlled pilot study is warranted to further evaluate ACCENT in patients with AMI cancers.

Indexed as

Adaptation, PsychologicalCognitive Behavioral TherapyExistentialismNeoplasmsAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedUncertaintyacceptance and commitment therapyadvanced, incurable and metastatic cancerscognitive behavioral therapycognitive existential therapygroup therapypragmatic feasibility studypsychological interventionuncertainty

Identifiers

PMID40155347
PMCPMC11953013

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