Evidence map›Paper›PMID 40155150›Full record

ArticleJACC. Case reports2025

Mitral Valve Aspergillus Endocarditis With Aortal Embolization in an Immunocompetent Patient.

Ling Zhu, Wenjie Huang, Dillon Guo Dong Yeo, Yen Ee Tan, Tze Tec Chong, Thuan Tong Tan, Yeow Leng Chua

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Journal of fungi (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ling ZhuDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore. Electronic address: zhu.ling1@singhealth.com.sg.
Wenjie HuangDepartment of Microbiology, Singapore General Hospital, Singapore.
Dillon Guo Dong YeoDepartment of Infectious Diseases, Singapore General Hospital, Singapore.
Yen Ee TanDepartment of Microbiology, Singapore General Hospital, Singapore.
Tze Tec ChongDepartment of Vascular Surgery, Singapore General Hospital, Singapore.
Thuan Tong TanDepartment of Infectious Diseases, Singapore General Hospital, Singapore.
Yeow Leng ChuaDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus endocarditis is a rare condition. The clinical presentation is often atypical and insidious, resulting in delayed diagnosis and challenges in management. We report a case of native mitral valve Aspergillus endocarditis in an immunocompetent patient, with rare aortal embolization, who was managed in a multidisciplinary approach. Evidence for Aspergillus endocarditis is limited, and prospective data are unlikely to be available because of the low incidence of the disease. This case report adds great value to the current published case series to provide experience for clinicians when tackling similar conditions. Aspergillus endocarditis is rare but fatal. Cardiac surgery improves early survival, but long-term outcomes remain dismal. An endocarditis team with a multimodality approach is paramount to manage this difficult-to-treat disease.

Indexed as

antifungal treatmentaortal embolizationAspergillus endocarditisAspergillus fumigatuscardiac surgerymitral regurgitation

Identifiers

PMID40155150
PMCPMC12014325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.