Evidence map›Paper›PMID 40155134›Full record

ArticleJACC. Case reports2025

Simultaneous Transcatheter Pulmonary and Tricuspid Valve Replacement in Carcinoid Heart Disease.

Varius Dannenberg, Caglayan Demirel, Markus Raderer, Barbara Kiesewetter, Lukas Reider, Anna Bartunek, Martin Andreas, Daniel Zimpfer, Jutta Bergler-Klein, Christian Hengstenberg and 1 more

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Varius DannenbergDepartment for Internal Medicine II, Clinical Division of Cardiology, Medical University of Vienna, Vienna, Austria.
Caglayan DemirelDepartment for Internal Medicine II, Clinical Division of Cardiology, Medical University of Vienna, Vienna, Austria.
Markus RadererDepartment of Internal Medicine I, Clinical Division of Oncology, Medical University of Vienna, Vienna, Austria.
Barbara KiesewetterDepartment of Internal Medicine I, Clinical Division of Oncology, Medical University of Vienna, Vienna, Austria.
Lukas ReiderDepartment of Interventional Radiology, Medical University of Vienna, Vienna, Austria.
Anna BartunekDepartment of Anaesthesiology, General Intensive Care and Pain Medicine, Division of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University Vienna, Vienna, Austria.
Martin AndreasDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Daniel ZimpferDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Jutta Bergler-KleinDepartment for Internal Medicine II, Clinical Division of Cardiology, Medical University of Vienna, Vienna, Austria.
Christian HengstenbergDepartment for Internal Medicine II, Clinical Division of Cardiology, Medical University of Vienna, Vienna, Austria.
Philipp E BartkoDepartment for Internal Medicine II, Clinical Division of Cardiology, Medical University of Vienna, Vienna, Austria. Electronic address: philippemanuel.bartko@meduniwien.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuroendocrine tumors can cause carcinoid heart disease, often presenting with pulmonary and tricuspid regurgitation. Valvular pathology and right heart failure can influence prognosis more than the tumor itself. Given high surgical risk, prolonged recovery, and limited life expectancy, interventional valve replacement is a strong alternative. CASE SUMMARY: We present a patient with severe pulmonary and torrential tricuspid regurgitation caused by carcinoid heart disease. Despite stable neuroendocrine tumor control, the patient developed progressive right heart failure, requiring urgent valve therapy. Simultaneous transcatheter pulmonary and tricuspid valve replacements were performed, almost eliminating tricuspid and pulmonary regurgitation. DISCUSSION: Right heart valve failure is frequent in carcinoid heart disease and significantly impacts outcomes. Although surgical valve replacement remains the standard, transcatheter approaches provide an effective, less invasive alternative for high-risk patients, offering symptom relief and excellent results. TAKE-HOME MESSAGE: Simultaneous interventional valve replacement in carcinoid heart disease is feasible and effective.

Indexed as

carcinoid heart diseaseechocardiographyneuroendocrine tumorpulmonary valvetricuspid valvevalve replacement

Identifiers

PMID40155134
PMCPMC12014326

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.