Evidence map›Paper›PMID 40154727›Full record

ArticleExperimental eye research2025

A biometric survey of known and prospective murine models of posterior microphthalmia-nanophthalmia.

Navdeep Gogna, Jai Pinkney, Lisa Stone, Mhd Mustafa Khorzom, Fuxin Zhao, Gayle B Collin, Juergen K Naggert, Mark P Krebs, Patsy M Nishina

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Polyunsaturated fatty acid metabolism in the retinal pigment epithelium and its association with outer retinal disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Navdeep GognaThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Jai PinkneyThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Lisa StoneThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Mhd Mustafa KhorzomThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Fuxin ZhaoThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Gayle B CollinThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Juergen K NaggertThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Mark P KrebsThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA. Electronic address: mark.krebs@jax.org.
Patsy M NishinaThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA. Electronic address: patsy.nishina@jax.org.

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
RETINAL DISEASE: MOLECULAR BASIS AND PATHOPHYSIOLOGYR01EY011996 · NEI · JACKSON LABORATORY · PI Patsy M Nishina · 1998 to 2026
$12.4M
Identifying Shared Pathogenic Networks and Molecular Targets Underlying Retinal Pigmented Epithelial Associated DiseaseR01EY027860 · NEI · JACKSON LABORATORY · PI CARTER, GREGORY W, NISHINA, PATSY M · 2017 to 2020
$2.4M
Genetic Modifiers of Enhanced S-cone Syndrome –Role of the External Limiting MembraneR01EY028561 · NEI · JACKSON LABORATORY · PI NAGGERT, JUERGEN K. · 2018 to 2022
$2.2M
NCI NIH HHS P30 CA034196NEI NIH HHS R01 EY011996NEI NIH HHS R01 EY027860NEI NIH HHS R01 EY028561
6 · The paper itself

Abstract

Posterior microphthalmia and nanophthalmia are related genetic conditions that disrupt ocular growth. Here, we conducted a biometric analysis of mouse models to assess shared features of these diseases. Three known microphthalmia alleles (Mfrp

Indexed as

Disease Models, AnimalMicrophthalmosAnimalsAxial Length, EyeBiometryFemaleMaleMiceMice, Inbred C57BLProspective StudiesTomography, Optical CoherenceAxial lengthCorneal radius of curvatureMACNanophthalmia (nanophthalmos)Ocular biometryOptical coherence tomographyPosterior microphthalmia (microphthalmos)

Identifiers

PMID40154727
PMCPMC12906678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.