Evidence map›Paper›PMID 40154101›Full record

ArticleDrug and alcohol dependence2025

Perceived racial discrimination and tobacco and cannabis use in pregnant Black Americans: The mediating role of depressive symptoms.

Jocelyn Stanfield, Anne L Dunlop, Dana Boyd Barr, Elizabeth J Corwin, Parinya Panuwet, Volha Yakimavets, Patricia A Brennan

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jocelyn StanfieldDepartment of Psychology, Emory University, 36 Eagle Row, Atlanta, GA, USA. Electronic address: jocelyn.stanfield@emory.edu.
Anne L DunlopDepartment of Gynecology and Obstetrics, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA, USA.
Dana Boyd BarrGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, GA, USA.
Elizabeth J CorwinSchool of Nursing, Columbia University, 560 W 168th St, New York, NY, USA.
Parinya PanuwetGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, GA, USA.
Volha YakimavetsGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, GA, USA.
Patricia A BrennanDepartment of Psychology, Emory University, 36 Eagle Row, Atlanta, GA, USA.

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
The Impact of the Intrauterine and Early Childhood Environments on Neurocognitive and Metabolic Development in African American Youth: Focus on the Gut-Brain AxisUH3OD023318 · OD · EMORY UNIVERSITY · PI PATRICIA A BRENNAN, ANNE Lang DUNLOP · 2018 to 2026
$9.0M
Maternal Stress and the Gut-Brain Axis in African American InfantsR01MD009746 · NIMHD · EMORY UNIVERSITY · PI BRENNAN, PATRICIA A, CORWIN, ELIZABETH JEANNE · 2015 to 2019
$3.6M
Microbiome, Environment, and Neurodevelopmental Delay (MEND)P50ES026071 · NIEHS · EMORY UNIVERSITY · PI MCCAULEY, LINDA A. · 2015 to 2018
$3.3M
Biobehavioral Determinants of the Microbiome and Preterm Birth in Black WomenR01NR014800 · NINR · EMORY UNIVERSITY · PI CORWIN, ELIZABETH JEANNE, DUNLOP, ANNE LANG · 2013 to 2017
$2.8M
Maintenance and Enhancement of the Atlanta African American Maternal-Child Cohort: Exposome Profiling via High-resolution Metabolomics and Integration of Microbiome-Metabolome-Epigenome DataR24ES029490 · NIEHS · EMORY UNIVERSITY · PI ANNE Lang DUNLOP, Dean Paul Jones · 2018 to 2026
$2.4M
Maintenance and Enhancement of the Atlanta African American Maternal-Child CohortU24ES029490 · NIEHS · EMORY UNIVERSITY · PI DUNLOP, ANNE LANG, JONES, DEAN PAUL · 2024 to 2025
$743k
NIEHS NIH HHS P30 ES019776NIEHS NIH HHS P50 ES026071NIEHS NIH HHS R24 ES029490NIEHS NIH HHS U24 ES029490NIH HHS UH3 OD023318NIMHD NIH HHS R01 MD009746NINR NIH HHS R01 NR014800
6 · The paper itself

Abstract

The objective of the current study was to assess the relationships between perceived racial discrimination, symptoms of depression, and tobacco and cannabis use in a sample of pregnant Black Americans. We collected data from 668 pregnant participants, in Atlanta, GA, once at 8- to 14- weeks' gestation and again at 24- to 30-weeks' gestation. We administered the Timeline Follow-back Interview to assess self-reported tobacco and cannabis use and measured metabolites of nicotine (cotinine) and cannabis (11-nor-9-carboxy-Δ9-tetrahydrocannabinol) from urine samples. Participants described depressive symptoms using the Edinburgh Postnatal Depression Scale. They also reported instances of racial discrimination throughout their lifetimes via the Krieger Experiences of Discrimination scale. Self-perceived racial discrimination was significantly related to increased tobacco use and urinary cotinine levels during pregnancy, while controlling for potential confounds. Race-based discrimination also impacted self-reported tobacco and cannabis use later in pregnancy through increased depressive symptoms. To our knowledge, this study is the first to investigate whether depressive symptoms mediate the influence of racial discrimination on substance use among pregnant Black people. Our findings have significant implications for smoking-cessation interventions, which should account for the interconnection between racial stress and mental health.

Indexed as

Black or African AmericanDepressionMarijuana UsePregnancy ComplicationsRacismSmokingAdolescentAdultCotinineFemaleHumansPregnancyYoung AdultCotinineCannabisDepressionDiscriminationLongitudinalPregnancyTobacco

Identifiers

PMID40154101
PMCPMC12050204

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.