Evidence map›Paper›PMID 40153543›Full record

Trial reportAmerican journal of respiratory and critical care medicine2025

Dual α

Sydney B Montesi, Gregory P Cosgrove, Scott M Turner, Iris Y Zhou, Nikos Efthimiou, Antonia Susnjar, Ciprian Catana, Caroline Fromson, Annie Clark, Martin Decaris and 3 more

Abstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Peptide Angio-3 Attenuates Pulmonary Fibrosis Via Modulation of the Coagulation Factor Xa-Protease-Activated Receptor-1 Signaling Axis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. The importance of mechanical forces in chronic respiratory diseases.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  14. Review
  15. Integrated single-cell TCR analysis across tissue identifies GZMKInternational journal of biological sciences · 2026
    Article
  16. Chest Imaging with a Collagen-Binding Probe-A Human Hydroxyproline Assay?American journal of respiratory and critical care medicine · 2025
    Article
  17. LangerinClinical, cosmetic and investigational dermatology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Sydney B MontesiDivison of Pulmonary and Critical Care Medicine and.
Gregory P CosgrovePliant Therapeutics, Inc., South San Francisco, California.
Scott M TurnerFormer employee of Pliant Therapeutics, Inc., South San Francisco, California; and.
Iris Y ZhouInstitute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.
Nikos EfthimiouHarvard Medical School, Boston, Massachusetts.ORCID 0000-0003-1947-5033
Antonia SusnjarHarvard Medical School, Boston, Massachusetts.
Ciprian CatanaInstitute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-3249-5971
Caroline FromsonDivison of Pulmonary and Critical Care Medicine and.
Annie ClarkPliant Therapeutics, Inc., South San Francisco, California.
Martin DecarisPliant Therapeutics, Inc., South San Francisco, California.
Chris N BarnesPliant Therapeutics, Inc., South San Francisco, California.
Éric A LefebvrePliant Therapeutics, Inc., South San Francisco, California.
Peter CaravanInstitute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.

Funding

PET-MR Imaging of pulmonary fibrosisR01HL153606 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D, CATANA, CIPRIAN · 2021 to 2025
$4.1M
Vascular Leak and Outcomes in IPFK23HL150331 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MONTESI, SYDNEY · 2020 to 2024
$887k
Quantitative MRI-PET Imaging of Pulmonary FibrosisK25HL148837 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ZHOU, IRIS YUWEN · 2020 to 2023
$686k
Inductively Coupled Plasma Mass SpectrometerS10OD032138 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2022 to 2022
$598k
Electronics Upgrade for 11.7 TS10OD025234 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2018 to 2018
$595k
Automation Equipment for Human PET Radiotracer ProductionS10OD028499 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2021 to 2021
$325k
NHLBI NIH HHS K23 HL150331NHLBI NIH HHS K25 HL148837NHLBI NIH HHS R01 HL153606NIH HHS S10 OD025234NIH HHS S10 OD028499NIH HHS S10 OD032138Pliant Therapeutics, Inc
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antigens, NeoplasmCollagen Type IIdiopathic Pulmonary FibrosisIntegrinsAgedDouble-Blind MethodFemaleHumansLungMaleMiddle AgedPositron-Emission TomographyTreatment OutcomeAntigens, NeoplasmCollagen Type Iintegrin alphavbeta6Integrinsbexotegrastcollagen type Ifibrotic diseaseidiopathic pulmonary fibrosispositron emission tomography imaging

Identifiers

PMID40153543
PMCPMC12264702

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.