Evidence map›Paper›PMID 40153482›Full record

ArticleJournal of proteome research2025

Microvesicles Derived from Human Bronchial Epithelial Cells Regulate Macrophage Activation During

Carlyn M Guthrie, Amber C Meeker, Ashton E Self, Aidaly Ramos-Leyva, Olivia L Clark, Stephen K Kotey, Steven D Hartson, Yurong Liang, Lin Liu, Xuejuan Tan and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carlyn M GuthrieDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Amber C MeekerDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Ashton E SelfDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Aidaly Ramos-LeyvaDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Olivia L ClarkDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Stephen K KoteyDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Steven D HartsonDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Yurong LiangOklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Lin LiuOklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Xuejuan TanDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Yong ChengDepartment of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States.ORCID 0000-0001-9535-5741

Funding

Pilot Project Grant ProgramP30GM149368 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI LIN LIU · 2023 to 2026
$5.5M
The role of FENDRR in host defense against Mycobacterium tuberculosis infectionR01AI173180 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI CHENG, YONG, LIU, LIN · 2022 to 2025
$3.0M
Genome-wide screening for host lncRNAs regulating host defense against Mycobacterial infection in macrophagesR21AI166118 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI CHENG, YONG, LIU, LIN · 2022 to 2023
$411k
NIAID NIH HHS R01 AI173180NIAID NIH HHS R21 AI166118NIGMS NIH HHS P30 GM149368
6 · The paper itself

Abstract

Intercellular communication is important for host immunity in response to bacterial infections. Nontuberculous mycobacterium (NTM), such as

Indexed as

BronchiCell-Derived MicroparticlesEpithelial CellsMacrophage ActivationMycobacterium abscessusMycobacterium Infections, NontuberculousHumansIntercellular Adhesion Molecule-1MacrophagesProteomicsTHP-1 CellsICAM1 protein, humanIntercellular Adhesion Molecule-1epithelial cellsextracellular vesiclesintercellular communicationmacrophagesmicrovesiclesMycobacterium abscessusproteomics

Identifiers

PMID40153482
PMCPMC12053935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.