Evidence map›Paper›PMID 40153431›Full record

ReviewPacing and clinical electrophysiology : PACE2025

First Experience Using a Novel Variable Loop Catheter for Mapping and Pulsed Field Ablation of Atrial Fibrillation.

Thomas Fink, Vanessa Sciacca, Kevin Bannmann, Maximilian Moersdorf, Sebastian Beyer, Alessandro Parlato, Denise Guckel, Mustapha El Hamriti, Moneeb Khalaph, Martin Braun and 6 more

Abstract readReview
In one paragraph

Review in Pacing and clinical electrophysiology : PACE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Zero/Low-fluoroscopy pulsed-field ablation approach: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  5. Real-world strategies for pulsed field ablation using a variable-loop circular catheter: a compendium of best practices from early adopters.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Thomas FinkClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.ORCID 0000-0002-6665-7326
Vanessa SciaccaClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Kevin BannmannClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Maximilian MoersdorfClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Sebastian BeyerClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Alessandro ParlatoClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Denise GuckelClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.ORCID 0000-0003-1470-7157
Mustapha El HamritiClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Moneeb KhalaphClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Martin BraunClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Maxim DidenkoClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Guram ImnadzeClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Dominik LinzDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands.
Kevin VernooyDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands.
Philipp SommerClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.
Christian SohnsClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany.ORCID 0000-0003-0490-5862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsA novel multielectrode variable loop catheter (VLC) has been introduced for atrial fibrillation (AF) ablation enabling 3D electroanatomic mapping and concomitant pulsed field ablation (PFA). This study sought to investigate the VLC under routine clinical conditions for AF ablation.

methodsConsecutive patients with symptomatic AF undergoing first-time AF ablation were prospectively enrolled. All procedures were carried out using the VLC. Electroanatomic mapping pre and post-ablation was conducted with the VLC and a high-density multipolar mapping catheter. The general ablation protocol consisted of four ablation pulses per pulmonary vein (PV). All procedures were conducted in conscious sedation.

resultsForty-five patients (mean age 66.3 ± 6.1 years, 68.9% paroxysmal AF) were analyzed. Procedure duration was 66.3 ± 13.1 min. Acute pulmonary vein isolation (PVI) was achieved in 45 patients without periprocedural complications. Remapping after the initial 16 ablation pulses revealed sustained electrical conduction to at least one PV in six patients (13.3%). Repeat ablation was conducted and with an average of 7.5 ± 4.5 additional pulses. PV intubation during mapping was achieved in 168/180 PVs with the VLC (93.3%) and in 180/180PVs (100%) with the high-density mapping catheter (p < 0.001). Incomplete PV intubation during mapping did not result in incomplete PVI, as demonstrated by remapping utilizing the high-density mapping catheter. Adequate correlation between left atrial post-ablation remapping of low voltage areas and ablated regions was demonstrated in all patients.

conclusionPFA-guided AF ablation using the novel VLC is safe and effective. The integration into a 3D-electroanatomic mapping system enables adequate mapping during PFA procedures.

Indexed as

Atrial FibrillationBody Surface Potential MappingCatheter AblationAgedEquipment DesignFemaleHumansMaleMiddle AgedProspective StudiesPulmonary VeinsTreatment Outcomeatrial fibrillationhigh‐density mappinglaboratory analysispulmonary vein isolationworkflow optimization

Identifiers

PMID40153431
PMCPMC12063197

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.